{"id":"W3111905777","doi":"10.4269/ajtmh.20-0917","title":"Safety and Immunogenicity of Live Oral Cholera Vaccine CVD 103-HgR in Children Aged 2–5 Years in the United States","year":2020,"lang":"en","type":"article","venue":"American Journal of Tropical Medicine and Hygiene","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Emergent BioSolutions (Canada)","funders":"","keywords":"Reactogenicity; Seroconversion; Medicine; Immunogenicity; Placebo; Adverse effect; Vaccination; Cholera vaccine; Cholera; Immunology; Internal medicine; Pediatrics; Virology; Antibody; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002110505,0.0005156273,0.000978166,0.0001994433,0.000326391,0.0002994127,0.0002994087,0.0006843901,0.001098835],"category_scores_gemma":[0.00108022,0.0003630328,0.0006993649,0.0002464698,0.0004571481,0.0003042931,0.0002162587,0.0009437118,0.0001967191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004146186,"about_ca_system_score_gemma":0.001210097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002443931,"about_ca_topic_score_gemma":0.003822132,"domain_scores_codex":[0.999262,0.0004300211,0.00004898856,0.00008098059,0.0001000403,0.00007793371],"domain_scores_gemma":[0.9993492,0.0001302713,0.0002197458,0.00004365599,0.00006765158,0.0001894416],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5873793,0.02876989,0.2040426,0.001483001,0.001589557,0.0007254102,0.0009196589,0.001373936,0.05030292,0.0002004415,0.002007255,0.1212061],"study_design_scores_gemma":[0.08394483,0.5815459,0.3264192,0.0001034959,0.0007412341,0.000354567,0.0002448121,0.0003843572,0.004402492,0.00005141118,0.001786371,0.00002122119],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984934,0.0008011157,0.00008762482,0.00005063844,0.00001525678,0.0001748174,0.0001493895,0.00001018357,0.0002176189],"genre_scores_gemma":[0.9977136,0.0007124538,0.0003494041,0.0002162536,0.00002852952,0.0002830279,0.000431708,0.000003041077,0.0002620692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002443931,"threshold_uncertainty_score":0.01116157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01151784617153749,"score_gpt":0.2744453682586492,"score_spread":0.2629275220871117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}