{"id":"W3111948799","doi":"10.3390/cancers12123650","title":"TGF-β Mediated Immune Evasion in Cancer—Spotlight on Cancer-Associated Fibroblasts","year":2020,"lang":"en","type":"article","venue":"Cancers","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Tumor microenvironment; Cancer-Associated Fibroblasts; Carcinogenesis; Cancer research; Extracellular matrix; Transforming growth factor; Immune system; Metastasis; Transforming growth factor beta; Cancer; Immune checkpoint; Signal transduction; Cancer cell; Tumor progression; Biology; Cell biology; Immunology; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000741408,0.0002292472,0.0002440783,0.00004821924,0.00006525369,0.00001596354,0.0002865384,0.0001859776,0.0001587657],"category_scores_gemma":[0.0002627629,0.0002329184,0.0000939874,0.0002985806,0.00006778116,0.000004911999,0.00007636061,0.0001598236,0.00002245852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006533319,"about_ca_system_score_gemma":0.0010201,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001219767,"about_ca_topic_score_gemma":0.001282764,"domain_scores_codex":[0.9985486,0.00007452789,0.0002848933,0.0005027814,0.000215714,0.0003734355],"domain_scores_gemma":[0.9993243,0.00002715109,0.0001445763,0.0002309053,0.00007295808,0.0002000606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007465192,0.00005311422,0.006559445,0.00007065664,0.000136884,0.00001858462,0.0003423507,0.03338145,0.9422482,0.000006232568,0.01445366,0.00198292],"study_design_scores_gemma":[0.002750989,0.0006124003,0.01804714,0.0004657058,0.00004607617,4.91492e-7,0.0001165227,0.001761307,0.9248168,0.000009243775,0.05072627,0.0006470226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914851,0.006443947,0.000009508259,0.0009181993,0.0003227122,0.0002410047,0.0001822251,0.00005737697,0.0003399492],"genre_scores_gemma":[0.9959953,0.0008626207,0.00001534016,0.002242414,0.000289868,0.0001439504,0.000243546,0.00005003907,0.000156893],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03627261,"threshold_uncertainty_score":0.9498136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01703762344509704,"score_gpt":0.2707499515946146,"score_spread":0.2537123281495176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}