{"id":"W3112102990","doi":"10.1002/alz.041129","title":"Overview of dominantly inherited AD and top‐line DIAN‐TU results of solanezumab and gantenerumab","year":2020,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Vancouver Coastal Health Research Institute; McGill University Health Centre","funders":"","keywords":"Medicine; Dosing; Randomized controlled trial; Population; Clinical trial; Oncology; Personalized medicine; Internal medicine; Bioinformatics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01092163,0.0009515012,0.001750449,0.00192023,0.0003967074,0.003073014,0.000971534,0.001074685,0.004994101],"category_scores_gemma":[0.006614635,0.000480651,0.003016767,0.001632013,0.0004799361,0.001596147,0.000821589,0.002539088,0.001569947],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003406063,"about_ca_system_score_gemma":0.003200934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002360522,"about_ca_topic_score_gemma":0.004311485,"domain_scores_codex":[0.9961236,0.001746767,0.0006159956,0.0003991377,0.00077858,0.000335893],"domain_scores_gemma":[0.9942238,0.002278774,0.001028534,0.0003087046,0.001421996,0.0007382322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01217344,0.0005461156,0.002270416,0.01035198,0.001757388,0.0001426687,0.0001196203,0.0009097948,0.003836459,0.005348165,0.03380679,0.9287371],"study_design_scores_gemma":[0.01313937,0.02412759,0.02530174,0.01884743,0.007282098,0.002029052,0.0002015196,0.00138632,0.007828739,0.006974764,0.8927129,0.000168507],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02535611,0.9012235,0.006117428,0.01291977,0.002029715,0.001601438,0.005680425,0.000314392,0.04475724],"genre_scores_gemma":[0.1869929,0.7328486,0.02187081,0.02384897,0.003692616,0.004046536,0.01364003,0.0003803606,0.01267912],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01092163,"threshold_uncertainty_score":0.05775976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06659721003455309,"score_gpt":0.3265541590579808,"score_spread":0.2599569490234277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}