{"id":"W3112122876","doi":"10.1039/d0sc03304a","title":"Pyridylic anions are soft nucleophiles in the palladium-catalyzed C(sp<sup>3</sup>)–H allylation of 4-alkylpyridines","year":2020,"lang":"en","type":"article","venue":"Chemical Science","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke; Centre in Green Chemistry and Catalysis; York University","funders":"York University; Compute Canada; Natural Sciences and Engineering Research Council of Canada; F. Hoffmann-La Roche; Roche","keywords":"Nucleophile; Palladium; Catalysis; Chemistry; Medicinal chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005221053,0.0001581175,0.0002166374,0.00005811239,0.0001165777,0.00006235163,0.0008879617,0.00009183842,0.0007266975],"category_scores_gemma":[0.003185782,0.0001249047,0.00008666534,0.001492502,0.0006914595,0.0002339887,0.0001882786,0.0002035947,0.00002907294],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008497723,"about_ca_system_score_gemma":0.0001548563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000256695,"about_ca_topic_score_gemma":0.000002582426,"domain_scores_codex":[0.9980891,0.00002221439,0.0003998134,0.0004830353,0.0007190902,0.0002868012],"domain_scores_gemma":[0.9986872,0.0004134649,0.0001786083,0.0003961821,0.0001664332,0.0001581086],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002441745,0.00006788201,0.005388327,0.00007084777,0.000004755969,0.000002255449,0.001241594,0.000897711,0.9901553,0.0008026615,0.0006530199,0.0006912113],"study_design_scores_gemma":[0.0006984863,0.0000111323,0.005782933,0.00008177743,0.00003024363,0.00001784089,0.001543161,0.0557263,0.9300747,0.001357332,0.004335793,0.0003403054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991655,0.0000760067,0.0008823556,0.004299506,0.00003651159,0.0001025951,0.00003753153,0.00006908474,0.002841396],"genre_scores_gemma":[0.9983497,0.000008884324,0.0008720977,0.0004409045,0.0002138473,0.00001608693,0.00005906341,0.00001263809,0.00002682345],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06008062,"threshold_uncertainty_score":0.7956828,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03526612590853518,"score_gpt":0.2806789278669226,"score_spread":0.2454128019583874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}