{"id":"W3112148259","doi":"10.3390/cells9122682","title":"TRPML1—Emerging Roles in Cancer","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Calcium signaling and nucleotide metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Nova Scotia Health Research Foundation","keywords":"Neurodegeneration; Autophagy; Cell biology; Transient receptor potential channel; Biology; Neuroscience; Homeostasis; Medicine; Biochemistry; Pathology; Receptor; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000511884,0.000270393,0.0002811438,0.0005949436,0.0002369037,0.001051161,0.0004916019,0.0008883757,0.001525212],"category_scores_gemma":[0.0003941117,0.00008116786,0.0001761103,0.000498509,0.0007098493,0.001237026,0.0006645942,0.001202501,0.0004547674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007405318,"about_ca_system_score_gemma":0.0005514769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002632551,"about_ca_topic_score_gemma":0.0003493407,"domain_scores_codex":[0.9998941,0.0000194321,0.000009275209,0.00002001516,0.00003100849,0.00002611991],"domain_scores_gemma":[0.9998205,0.00003529476,0.00003823352,0.000007236309,0.00003240597,0.0000662503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0007650675,0.0001627161,0.003463911,0.002333299,0.00005608562,0.002574007,0.0002890157,0.0009328189,0.07990527,0.06869472,0.0377401,0.8030831],"study_design_scores_gemma":[0.00008651725,0.0006771548,0.007569817,0.0006715008,0.00006531386,0.006885525,0.0004894797,0.001479485,0.02291808,0.03472029,0.9243979,0.00003889376],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01461933,0.9550766,0.003032069,0.01976898,0.001100894,0.00001408578,0.0001267082,0.0001630704,0.006098154],"genre_scores_gemma":[0.1437985,0.8404026,0.004174422,0.003783907,0.003361738,0.00003196263,0.0001733033,0.00001970188,0.004253947],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001525212,"threshold_uncertainty_score":0.005372941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01581063713614497,"score_gpt":0.2612289610981661,"score_spread":0.2454183239620211,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}