{"id":"W3112175219","doi":"10.1200/jco.20.02529","title":"Total Body Irradiation or Chemotherapy Conditioning in Childhood ALL: A Multinational, Randomized, Noninferiority Phase III Study","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":329,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Alberta Children's Hospital","funders":"","keywords":"Medicine; Total body irradiation; Cumulative incidence; Busulfan; ThioTEPA; Internal medicine; Surgery; Hematopoietic stem cell transplantation; Population; Treosulfan; Transplantation; Chemotherapy; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007604293,0.001532278,0.002381451,0.0005134756,0.0005481226,0.0008978992,0.001013073,0.001591809,0.004288155],"category_scores_gemma":[0.004055303,0.0006379815,0.002298956,0.000724621,0.001629604,0.0008732154,0.0005168134,0.002234251,0.0005244951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000978146,"about_ca_system_score_gemma":0.002611286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001054884,"about_ca_topic_score_gemma":0.002395558,"domain_scores_codex":[0.9966301,0.002666998,0.000140157,0.0002220346,0.0001558979,0.0001847927],"domain_scores_gemma":[0.9974533,0.0008149392,0.0007384181,0.0002808244,0.0001500265,0.0005625078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9596865,0.01578535,0.001937473,0.0006936911,0.00114676,0.00004025033,0.00005879848,0.0005256067,0.002307747,0.0001317182,0.0008989135,0.01678717],"study_design_scores_gemma":[0.9121972,0.08419388,0.001620495,0.00004119565,0.0006275106,0.0000254158,0.00001452319,0.0002541843,0.0002828884,0.0001108957,0.0006223402,0.000009480387],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9748657,0.005561189,0.001766776,0.001041854,0.0005260176,0.01326004,0.001380417,0.00009792458,0.001500249],"genre_scores_gemma":[0.963299,0.005053317,0.004736929,0.002357619,0.0006741389,0.0202087,0.001559297,0.00003926655,0.002071763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007604293,"threshold_uncertainty_score":0.04021579,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09409068729701432,"score_gpt":0.4730154490263991,"score_spread":0.3789247617293848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}