{"id":"W3112175219","doi":"10.1200/jco.20.02529","title":"Total Body Irradiation or Chemotherapy Conditioning in Childhood ALL: A Multinational, Randomized, Noninferiority Phase III Study","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":329,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Alberta Children's Hospital","funders":"","keywords":"Medicine; Total body irradiation; Cumulative incidence; Busulfan; ThioTEPA; Internal medicine; Surgery; Hematopoietic stem cell transplantation; Population; Treosulfan; Transplantation; Chemotherapy; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004514709,0.0001443041,0.002064824,0.0001328067,0.000032256,0.00001304487,0.0000934177,0.0002393824,0.0005201869],"category_scores_gemma":[0.005093789,0.00010363,0.000362702,0.0001959445,0.0001024368,0.0001645088,0.00001157689,0.0008219245,0.00001574999],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001098641,"about_ca_system_score_gemma":0.001256767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001709281,"about_ca_topic_score_gemma":0.00001391032,"domain_scores_codex":[0.9951144,0.0008871467,0.003152852,0.0002103571,0.0004670175,0.0001682562],"domain_scores_gemma":[0.9936627,0.004092825,0.001535494,0.00008960001,0.0002915285,0.0003278355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8077893,0.0348224,0.0922417,0.0001510599,0.002348739,0.003956195,0.020205,0.0002320995,0.001401889,0.0002515284,0.0008730455,0.03572708],"study_design_scores_gemma":[0.7001473,0.01187854,0.2819172,0.0000907658,0.0005022252,0.0004570992,0.0008428884,0.003388204,0.00006977517,0.00005243294,0.0005474255,0.0001061808],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848175,0.00004875766,0.001955802,0.01107627,0.0004128171,0.00118429,0.000004308059,0.00001565765,0.000484596],"genre_scores_gemma":[0.9914016,0.000182904,0.003498398,0.004013455,0.0008247158,0.00001889192,0.00001422751,0.00001691113,0.00002886045],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1896755,"threshold_uncertainty_score":0.6098109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09409068729701432,"score_gpt":0.4730154490263991,"score_spread":0.3789247617293848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}