{"id":"W3112202821","doi":"10.1016/j.ygyno.2020.12.005","title":"Co-expression patterns of chimeric antigen receptor (CAR)-T cell target antigens in primary and recurrent ovarian cancer","year":2020,"lang":"en","type":"article","venue":"Gynecologic Oncology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of Victoria; University of British Columbia","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Chimeric antigen receptor; Medicine; Ovarian cancer; Antigen; Cancer research; Immunology; Cancer; Internal medicine; T cell; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004147706,0.0002132924,0.000829577,0.000158939,0.00005081869,0.000006669775,0.000180172,0.0003202396,0.01105566],"category_scores_gemma":[0.0001630822,0.0001789137,0.00008766481,0.0002957867,0.0001594238,0.00004878443,0.000141348,0.0005489422,0.00003212524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003501615,"about_ca_system_score_gemma":0.0005334711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001778968,"about_ca_topic_score_gemma":0.00005451796,"domain_scores_codex":[0.9978638,0.0003645722,0.0004868489,0.0005320785,0.0002599484,0.0004927125],"domain_scores_gemma":[0.9988599,0.0003445784,0.0002088678,0.0002337804,0.00008290775,0.0002699298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007161424,0.0004114206,0.3794725,0.000211403,0.00002974281,0.00008600941,0.0008166134,0.000005846044,0.5860498,0.000003013667,0.002172857,0.03002467],"study_design_scores_gemma":[0.005316291,0.005487062,0.7132031,0.00008092648,0.00003370551,0.00001459889,0.0004907396,0.0001603514,0.148959,0.0000197365,0.1259732,0.0002613446],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987126,0.001412655,0.00005230503,0.003370511,0.0003180104,0.001038168,0.00008238361,0.00004330777,0.006556642],"genre_scores_gemma":[0.9896196,0.005765618,0.001729425,0.001916729,0.0002203918,0.0001010189,0.0001272619,0.00003291114,0.0004871082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4370909,"threshold_uncertainty_score":0.9898484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03555750875034905,"score_gpt":0.3374122596685919,"score_spread":0.3018547509182429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}