{"id":"W3112303343","doi":"10.1093/neuonc/noaa215.172","title":"CTNI-05. NRG ONCOLOGY / RTOG 1119: PHASE II RANDOMIZED STUDY OF WHOLE BRAIN RADIOTHERAPY / STEREOTACTIC RADIOSURGERY WITH CONCURRENT LAPATINIB IN PATIENTS WITH BRAIN METASTASES FROM HER2-POSITIVE BREAST CANCER","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Medicine; Lapatinib; Radiosurgery; Internal medicine; Clinical endpoint; Breast cancer; Oncology; Pertuzumab; Adjuvant; Radiation therapy; Cancer; Trastuzumab; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006848774,0.0006472192,0.003393946,0.0002601435,0.0001173262,0.00001953244,0.0001998022,0.0001760634,0.0005911801],"category_scores_gemma":[0.0003597664,0.000441856,0.0002435979,0.0005846883,0.0004721167,0.0001623692,0.00009737729,0.0006464931,0.000004624929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005623574,"about_ca_system_score_gemma":0.0009742967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001496286,"about_ca_topic_score_gemma":0.0008391312,"domain_scores_codex":[0.992932,0.003633959,0.001161955,0.001046501,0.0006114478,0.0006141154],"domain_scores_gemma":[0.9931393,0.004666909,0.0009546938,0.0004665729,0.0002838864,0.000488666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6661256,0.05721477,0.0952864,0.0001404996,0.007003375,0.005099023,0.01928495,0.000253391,0.008392515,0.00002853959,0.009728578,0.1314424],"study_design_scores_gemma":[0.8487153,0.1050447,0.02125173,0.0002230307,0.002144446,0.0001783744,0.001811755,0.000414168,0.001013675,0.000003834822,0.01866718,0.000531826],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.960498,0.0004134165,0.0001410805,0.03118142,0.0003268342,0.00533057,0.002002367,0.00006069943,0.00004563464],"genre_scores_gemma":[0.9863178,0.00005619034,0.0004938424,0.01160766,0.0002054015,0.0006904291,0.0005076302,0.0001046435,0.00001645145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1825897,"threshold_uncertainty_score":0.9998033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01945880982942613,"score_gpt":0.3180389946175899,"score_spread":0.2985801847881638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}