{"id":"W3112303343","doi":"10.1093/neuonc/noaa215.172","title":"CTNI-05. NRG ONCOLOGY / RTOG 1119: PHASE II RANDOMIZED STUDY OF WHOLE BRAIN RADIOTHERAPY / STEREOTACTIC RADIOSURGERY WITH CONCURRENT LAPATINIB IN PATIENTS WITH BRAIN METASTASES FROM HER2-POSITIVE BREAST CANCER","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Medicine; Lapatinib; Radiosurgery; Internal medicine; Clinical endpoint; Breast cancer; Oncology; Pertuzumab; Adjuvant; Radiation therapy; Cancer; Trastuzumab; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001898297,0.001639402,0.001888946,0.0004584995,0.0004074739,0.0009619078,0.001077134,0.001126203,0.005263716],"category_scores_gemma":[0.001112096,0.0007833708,0.001232112,0.0005163634,0.001236586,0.0007122851,0.0003828236,0.00293272,0.001031753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001420274,"about_ca_system_score_gemma":0.002033401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002333952,"about_ca_topic_score_gemma":0.006643098,"domain_scores_codex":[0.9994733,0.0003015581,0.00002861169,0.00007890152,0.00003873015,0.00007900211],"domain_scores_gemma":[0.999384,0.00009468358,0.0001513097,0.00004003859,0.00003266182,0.0002972272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9324293,0.02893098,0.001394027,0.0005718418,0.0005585256,0.00005234155,0.00008086858,0.0006620004,0.007088823,0.0001417191,0.001163493,0.02692615],"study_design_scores_gemma":[0.7860863,0.2090221,0.00231048,0.00002601003,0.0003236882,0.00005065725,0.00002599178,0.0004746157,0.0007668453,0.00007740037,0.0008210437,0.00001490051],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893168,0.002043764,0.0004226338,0.0004490274,0.0002292394,0.004573352,0.0008078984,0.00009175565,0.002065516],"genre_scores_gemma":[0.982693,0.002752169,0.001706999,0.001172254,0.0003138376,0.005544055,0.001770966,0.00002944086,0.00401733],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005263716,"threshold_uncertainty_score":0.01760888,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01945880982942613,"score_gpt":0.3180389946175899,"score_spread":0.2985801847881638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}