{"id":"W3112334113","doi":"10.1089/aid.2020.0243","title":"Safety, Immune, and Antiviral Effects of Pegylated Interferon Alpha 2b Administration in Antiretroviral Therapy-Suppressed Individuals: Results of Pilot Clinical Trial","year":2020,"lang":"en","type":"article","venue":"AIDS Research and Human Retroviruses","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Immune system; Viral load; Immunology; Medicine; Immunotherapy; Interferon; Adverse effect; Pegylated interferon; Alpha interferon; Antiretroviral therapy; Virus; Virology; Internal medicine; Hepatitis C virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001861849,0.0002189101,0.0007335171,0.0003632907,0.0001829476,0.00004441251,0.0003008173,0.0002392375,0.00005380268],"category_scores_gemma":[0.001228907,0.0001773819,0.00009224694,0.0003487539,0.001444422,0.0001910967,0.0002854994,0.0008063712,0.00002286795],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002378739,"about_ca_system_score_gemma":0.0001836114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005778361,"about_ca_topic_score_gemma":0.00009202347,"domain_scores_codex":[0.9958412,0.001788215,0.001030437,0.0005337163,0.0002255833,0.0005808577],"domain_scores_gemma":[0.9976293,0.001595725,0.0002161098,0.0002977296,0.0001544876,0.0001066007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.2754067,0.002604931,0.2790184,0.0002814281,0.0006260509,0.00006488519,0.001031197,6.456526e-8,0.4200403,0.0005022149,0.0007877959,0.01963593],"study_design_scores_gemma":[0.1073247,0.1943058,0.4137243,0.0001774676,0.00002566231,0.000003261395,0.0002137269,7.79579e-7,0.2831179,0.0001521167,0.0007632177,0.0001910967],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99479,0.003244235,0.000002573248,0.0001348182,0.00007297192,0.001160303,0.0002152525,0.00002231445,0.0003574869],"genre_scores_gemma":[0.9973282,0.002130943,0.00002414263,0.00001845539,0.00004904687,0.00003128953,0.0002509229,0.00001911198,0.0001479054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1917009,"threshold_uncertainty_score":0.7233423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1268817916699619,"score_gpt":0.4077472529532326,"score_spread":0.2808654612832707,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}