{"id":"W3112334113","doi":"10.1089/aid.2020.0243","title":"Safety, Immune, and Antiviral Effects of Pegylated Interferon Alpha 2b Administration in Antiretroviral Therapy-Suppressed Individuals: Results of Pilot Clinical Trial","year":2020,"lang":"en","type":"article","venue":"AIDS Research and Human Retroviruses","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Immune system; Viral load; Immunology; Medicine; Immunotherapy; Interferon; Adverse effect; Pegylated interferon; Alpha interferon; Antiretroviral therapy; Virus; Virology; Internal medicine; Hepatitis C virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004381144,0.001066415,0.001458003,0.0002675285,0.0003765456,0.0007131861,0.0006440035,0.001324884,0.002359191],"category_scores_gemma":[0.002455696,0.0003613723,0.001086434,0.0003204534,0.001074712,0.0008770203,0.000341023,0.001897953,0.0004595448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005384904,"about_ca_system_score_gemma":0.0009314535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004050956,"about_ca_topic_score_gemma":0.0006217201,"domain_scores_codex":[0.9988503,0.0007756114,0.00007118969,0.00008468477,0.00008833159,0.0001297341],"domain_scores_gemma":[0.998394,0.000512791,0.0003262511,0.0001451263,0.0001509464,0.0004709514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8236306,0.0472813,0.01047267,0.0005437114,0.001030264,0.0004203701,0.0003570082,0.000880087,0.03352969,0.0001676529,0.00136256,0.08032413],"study_design_scores_gemma":[0.2987127,0.6811153,0.01486461,0.00003478428,0.0003400401,0.0002349205,0.00005372354,0.0006452831,0.002598353,0.0001627627,0.001217023,0.00002046741],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958918,0.001080483,0.0003990391,0.0002004319,0.00004573573,0.001252388,0.0003665833,0.00003869846,0.0007247989],"genre_scores_gemma":[0.994497,0.0006467788,0.001150415,0.0003606784,0.0001468199,0.001716563,0.0007830178,0.00001506282,0.0006837127],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004381144,"threshold_uncertainty_score":0.02316999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1268817916699619,"score_gpt":0.4077472529532326,"score_spread":0.2808654612832707,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}