{"id":"W3112371922","doi":"10.3389/fcimb.2020.602502","title":"Extracellular Vesicles in Trypanosomatids: Host Cell Communication","year":2020,"lang":"en","type":"review","venue":"Frontiers in Cellular and Infection Microbiology","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Université de Montréal","funders":"Canadian Institutes of Health Research; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Natural Sciences and Engineering Research Council of Canada; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Biology; Trypanosoma cruzi; Trypanosoma brucei; Kinetoplastida; Trypanosoma; Leishmania; Chagas disease; Host (biology); Protozoa; Immune system; African trypanosomiasis; Vector (molecular biology); Intracellular parasite; Extracellular vesicle; Parasite hosting; Trypanosomiasis; Immunology; Cell biology; Microbiology; Virology; Microvesicles; Ecology; Genetics; Malaria; Protozoal disease; Gene; microRNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003197393,0.0005834536,0.001248223,0.0003960842,0.0000886794,0.0000454775,0.0004129331,0.001093451,0.00001964067],"category_scores_gemma":[0.00008206532,0.0006159345,0.0003319523,0.0003918422,0.000303228,0.00001484308,0.0003375024,0.0007004331,0.00003083802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000124019,"about_ca_system_score_gemma":0.0001940398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000403375,"about_ca_topic_score_gemma":0.00003113652,"domain_scores_codex":[0.9966389,0.0009673926,0.0009583738,0.0009248526,0.00005828131,0.0004522313],"domain_scores_gemma":[0.9986652,0.00003771809,0.0004191895,0.0007100799,0.00003362882,0.0001342175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001956811,0.001385489,0.007015074,0.01632175,0.0004391133,0.000235942,0.0003732972,0.00002900315,0.4066849,0.0001859131,0.01702865,0.5501052],"study_design_scores_gemma":[0.0008082849,0.000134388,0.00002968566,0.0008548837,0.0001531008,0.00005888855,0.00004196318,0.00002806475,0.005925812,0.00007113576,0.9912731,0.0006207169],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005913227,0.9900165,0.002315548,0.00002087967,0.0005235421,0.0008818761,0.00007760887,0.00002723108,0.0002236162],"genre_scores_gemma":[0.003924818,0.9916144,0.001829413,0.00004333479,0.0001420043,0.0001201753,0.001900017,0.00009590009,0.0003299141],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9742444,"threshold_uncertainty_score":0.9996292,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01018295025315136,"score_gpt":0.2465520765655107,"score_spread":0.2363691263123593,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}