{"id":"W3112371922","doi":"10.3389/fcimb.2020.602502","title":"Extracellular Vesicles in Trypanosomatids: Host Cell Communication","year":2020,"lang":"en","type":"review","venue":"Frontiers in Cellular and Infection Microbiology","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Université de Montréal","funders":"Canadian Institutes of Health Research; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Natural Sciences and Engineering Research Council of Canada; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Biology; Trypanosoma cruzi; Trypanosoma brucei; Kinetoplastida; Trypanosoma; Leishmania; Chagas disease; Host (biology); Protozoa; Immune system; African trypanosomiasis; Vector (molecular biology); Intracellular parasite; Extracellular vesicle; Parasite hosting; Trypanosomiasis; Immunology; Cell biology; Microbiology; Virology; Microvesicles; Ecology; Genetics; Malaria; Protozoal disease; Gene; microRNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003152601,0.0007594089,0.0009707374,0.001389938,0.0002756652,0.001154694,0.000561585,0.001177016,0.004253563],"category_scores_gemma":[0.0004013576,0.0002106399,0.0003485066,0.001487604,0.0003762831,0.001407174,0.0007717116,0.001398271,0.002499528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005244636,"about_ca_system_score_gemma":0.0009270055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005365655,"about_ca_topic_score_gemma":0.0008012173,"domain_scores_codex":[0.9998789,0.00002137617,0.0000149983,0.00001984275,0.00004663128,0.00001830936],"domain_scores_gemma":[0.9998325,0.00007088952,0.00002638523,0.000004913782,0.00004263035,0.00002267032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008557345,0.00004773821,0.000154085,0.01894303,0.00006378381,0.0002419417,0.00009252723,0.0003193264,0.005795082,0.006564061,0.0267742,0.9409187],"study_design_scores_gemma":[0.000007475686,0.00006577459,0.0004505854,0.002107854,0.00004921326,0.0007501036,0.00004729251,0.0000518814,0.0007845679,0.001620307,0.9940529,0.00001208426],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001292391,0.998268,0.0001268284,0.000213313,0.0002599774,0.000003633164,0.00001994598,0.000007888875,0.0009710842],"genre_scores_gemma":[0.0009236356,0.9977382,0.0001377727,0.0001303057,0.0001612054,0.000004930255,0.00003789039,0.000001393792,0.0008647406],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004253563,"threshold_uncertainty_score":0.0142296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01018295025315136,"score_gpt":0.2465520765655107,"score_spread":0.2363691263123593,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}