{"id":"W3112404269","doi":"10.1016/j.jval.2020.08.173","title":"PCN36 Systematic Review of Treatments in Metastatic Castration-Resistant Prostate Cancer (mCRPC) with DNA Damage Repair Gene Mutation (DDRm)","year":2020,"lang":"en","type":"article","venue":"Value in Health","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"EVERSANA (Canada)","funders":"","keywords":"Medicine; Olaparib; Oncology; Internal medicine; Clinical trial; Taxane; Pembrolizumab; Prostate cancer; Cancer; Breast cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003423813,0.0009980648,0.006573663,0.004422006,0.0004023753,0.001571614,0.001038154,0.001004445,0.005859341],"category_scores_gemma":[0.01517203,0.0007059699,0.00988627,0.005308462,0.0005748757,0.0009344549,0.001133028,0.00118974,0.0003767756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00287717,"about_ca_system_score_gemma":0.005880269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02048529,"about_ca_topic_score_gemma":0.07170571,"domain_scores_codex":[0.9961384,0.001422798,0.001392868,0.0003906974,0.0005198115,0.0001353944],"domain_scores_gemma":[0.9940152,0.003573132,0.001622071,0.0001299411,0.0005312571,0.0001285028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.001150114,0.00002131356,0.001059,0.8977883,0.05076013,0.00007500457,0.0001028951,0.0002473057,0.0004568752,0.0001935306,0.003054212,0.04509129],"study_design_scores_gemma":[0.002375654,0.0007478686,0.01200385,0.5573064,0.3758602,0.0004056208,0.0001536095,0.0001555345,0.0003452884,0.0004969001,0.05007017,0.00007898381],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001147646,0.9968233,0.0001297814,0.0002118657,0.0001316211,0.0001719272,0.0009012562,0.000009602325,0.0004729922],"genre_scores_gemma":[0.03090337,0.9661435,0.0006240035,0.001025506,0.000097415,0.0002749668,0.0005866423,0.00001099756,0.0003334983],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02048529,"threshold_uncertainty_score":0.04073209,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08304421118659776,"score_gpt":0.3717929691983274,"score_spread":0.2887487580117296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}