{"id":"W3112434104","doi":"10.1016/j.cellsig.2020.109870","title":"Hydrogen sulfide guards myoblasts from ferroptosis by inhibiting ALOX12 acetylation","year":2020,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":false,"ca_institutions":"Science North; Health Sciences North; Laurentian University","funders":"Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Lipid peroxidation; Cell biology; Chemistry; Mitochondrion; Programmed cell death; Oxidative stress; GPX4; Reactive oxygen species; Lipid metabolism; Biochemistry; Apoptosis; Biology; Superoxide dismutase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001753726,0.0002580521,0.0002378481,0.00002726685,0.0001303275,0.00004342748,0.0003198501,0.000293061,0.0001016379],"category_scores_gemma":[0.0001586554,0.0002836848,0.0001451911,0.0001310115,0.00007240292,0.000007462133,0.000211643,0.000190674,0.00008012889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000253903,"about_ca_system_score_gemma":0.00004756782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003163798,"about_ca_topic_score_gemma":0.000003852582,"domain_scores_codex":[0.9982817,0.0001336641,0.0003663323,0.0006696322,0.0001836284,0.0003651049],"domain_scores_gemma":[0.999325,0.00004696608,0.0001559441,0.0002271707,0.00007587823,0.0001690083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006053865,0.00002062276,0.00136959,0.00000888764,0.00008570434,0.000006723304,0.0001488489,0.0006502273,0.995555,0.00001170532,0.001084278,0.0009978146],"study_design_scores_gemma":[0.0004575929,0.0001458966,0.00001884788,0.00001692493,0.00003168899,0.00000208054,0.00009435344,0.003372096,0.9804455,0.00009481158,0.01499947,0.0003207147],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9458068,0.003184775,0.04968733,0.0005057389,0.0001183595,0.0001563913,0.00004540255,0.00006048584,0.0004346871],"genre_scores_gemma":[0.9943996,0.0000836499,0.002184365,0.0009703159,0.0008869941,0.00001410802,0.001336561,0.00005852739,0.0000658533],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0485928,"threshold_uncertainty_score":0.9999616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01633670238506182,"score_gpt":0.2210138004724983,"score_spread":0.2046770980874365,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}