{"id":"W3112485457","doi":"10.1128/mbio.02250-20","title":"Intracellular Staphylococcus aureus Perturbs the Host Cell Ca <sup>2+</sup> Homeostasis To Promote Cell Death","year":2020,"lang":"en","type":"article","venue":"mBio","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Deutsche Forschungsgemeinschaft; University of Alberta","keywords":"Intracellular; Staphylococcus aureus; Homeostasis; Cell biology; Cell; Microbiology; Chemistry; Host (biology); Programmed cell death; Bacteria; Biology; Biochemistry; Apoptosis; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003036354,0.000553693,0.0006834535,0.0001231315,0.0003136908,0.0001369649,0.0006773886,0.0002581733,0.0007166138],"category_scores_gemma":[0.0002854451,0.0004079405,0.0003311834,0.0008057515,0.0001666802,0.0000988989,0.0002862617,0.0007858663,0.001674621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002218264,"about_ca_system_score_gemma":0.0003241491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002027644,"about_ca_topic_score_gemma":0.00001578013,"domain_scores_codex":[0.9967749,0.0001172022,0.0005846196,0.0009030395,0.000665321,0.000954979],"domain_scores_gemma":[0.9976262,0.0001299027,0.0001629515,0.001034869,0.0002554494,0.000790577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001243388,0.0006848273,0.003183346,0.0007924046,0.0001760199,0.00100545,0.0171281,0.000514271,0.8082309,0.00008555678,0.1629568,0.003999021],"study_design_scores_gemma":[0.001940005,0.001165528,0.001714391,0.0001421857,0.0003109733,0.00001061359,0.002015816,0.002035412,0.3902973,0.00002635739,0.5996078,0.0007335822],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9658405,0.002053953,0.00138954,0.02099881,0.0001475863,0.002333028,0.0002607387,0.0002297382,0.006746088],"genre_scores_gemma":[0.9812998,0.000163934,0.003312796,0.01122044,0.0006390915,0.00006979429,0.00005744467,0.0001320851,0.003104596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.436651,"threshold_uncertainty_score":0.9998372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01721403297742689,"score_gpt":0.2407974608412585,"score_spread":0.2235834278638316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}