{"id":"W3112485457","doi":"10.1128/mbio.02250-20","title":"Intracellular Staphylococcus aureus Perturbs the Host Cell Ca <sup>2+</sup> Homeostasis To Promote Cell Death","year":2020,"lang":"en","type":"article","venue":"mBio","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Deutsche Forschungsgemeinschaft; University of Alberta","keywords":"Intracellular; Staphylococcus aureus; Homeostasis; Cell biology; Cell; Microbiology; Chemistry; Host (biology); Programmed cell death; Bacteria; Biology; Biochemistry; Apoptosis; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001370594,0.000293793,0.0002793116,0.0001921593,0.0001542036,0.0004368971,0.0001519901,0.0003595335,0.002058959],"category_scores_gemma":[0.0001693872,0.0000959742,0.0002007879,0.0001083991,0.0002285398,0.0001698557,0.0002395397,0.0004774857,0.0006905869],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002797465,"about_ca_system_score_gemma":0.0002601462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005499995,"about_ca_topic_score_gemma":0.0008972645,"domain_scores_codex":[0.9998078,0.00002844906,0.0000157592,0.00002424272,0.00006754515,0.00005628001],"domain_scores_gemma":[0.9998825,0.00002558187,0.00002980686,0.00001671173,0.00001706592,0.000028332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002222601,0.0000292823,0.0003155512,0.00004542483,0.00000683585,0.0001790378,0.00002180287,0.00006255863,0.9966136,0.0002449235,0.0002157535,0.00204292],"study_design_scores_gemma":[0.00006266088,0.0007715992,0.009378952,0.00003072983,0.00002187876,0.001195787,0.0001977355,0.001796091,0.9793904,0.0005852603,0.006558762,0.00001019381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9774053,0.007414003,0.004164207,0.0009624313,0.0002442121,0.00004277792,0.0005230156,0.0002555262,0.008988598],"genre_scores_gemma":[0.9949955,0.001190817,0.001207429,0.0001799351,0.00002489156,0.00001756279,0.0001695714,0.00002092044,0.002193332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002058959,"threshold_uncertainty_score":0.006887913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01721403297742689,"score_gpt":0.2407974608412585,"score_spread":0.2235834278638316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}