{"id":"W3112504169","doi":"10.1016/j.stem.2020.11.013","title":"Cancer-Related Mutations Identified in Primed Human Pluripotent Stem Cells","year":2020,"lang":"en","type":"letter","venue":"Cell stem cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; Rosetrees Trust","keywords":"Induced pluripotent stem cell; Biology; Embryonic stem cell; Carcinogenesis; Stem cell; Genetics; Molecular biology; Cancer; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005897122,0.0003853422,0.0004791693,0.0005561509,0.000555869,0.0008247496,0.0005999334,0.009141799,0.002813603],"category_scores_gemma":[0.002054969,0.0003480736,0.0005927162,0.0003861963,0.0007529021,0.0004188494,0.0004008462,0.003585228,0.001046288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007325896,"about_ca_system_score_gemma":0.0003280866,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005918124,"about_ca_topic_score_gemma":0.0009359845,"domain_scores_codex":[0.9996178,0.00007809063,0.00005399377,0.00007349267,0.00008957506,0.00008704032],"domain_scores_gemma":[0.9990032,0.00066162,0.0001032112,0.0000629015,0.00006408062,0.0001048961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003771857,0.0004775794,0.01486857,0.0003741684,0.0002763203,0.4680554,0.0005473559,0.001552987,0.1591402,0.02341026,0.257858,0.06966743],"study_design_scores_gemma":[0.001602582,0.001706755,0.02396657,0.0001837041,0.0006202779,0.339556,0.0003951597,0.009263517,0.19544,0.02264607,0.4044408,0.000178559],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.4187581,0.01152066,0.009110105,0.4668095,0.03653719,0.0004410544,0.002860215,0.0008933836,0.05306991],"genre_scores_gemma":[0.699568,0.005471348,0.004479455,0.2331259,0.02337931,0.0002933724,0.0008000329,0.0002351088,0.03264751],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.009141799,"threshold_uncertainty_score":0.009412467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02029866241166117,"score_gpt":0.2597014960927492,"score_spread":0.239402833681088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}