{"id":"W3112539910","doi":"10.3390/microorganisms8121933","title":"The T3SS of Shigella: Expression, Structure, Function, and Role in Vacuole Escape","year":2020,"lang":"en","type":"review","venue":"Microorganisms","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Ottawa","keywords":"Shigella; Vacuole; Effector; Type three secretion system; Cell biology; Microbiology; Biology; Secretion; Shigella flexneri; Virulence; Escherichia coli; Gene; Cytoplasm; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001603209,0.000293654,0.0006344704,0.00004005105,0.0001258805,0.00003555578,0.0003683519,0.0002708636,0.0000159437],"category_scores_gemma":[0.0001553337,0.000191286,0.0001179932,0.0002157121,0.0001633226,0.000002136557,0.0006228281,0.0002926064,0.000004955592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000190322,"about_ca_system_score_gemma":0.0002177063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009264078,"about_ca_topic_score_gemma":0.00006161078,"domain_scores_codex":[0.9985791,0.0001870533,0.0003852494,0.0004378193,0.0001425685,0.0002682391],"domain_scores_gemma":[0.9992429,0.00005412569,0.0001796213,0.0003793329,0.00007429811,0.0000696953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005826782,0.00004550395,0.0001789583,0.003257604,0.0003431949,0.000005598633,0.0001093521,4.220038e-7,0.676986,0.00009364344,0.004799814,0.3141216],"study_design_scores_gemma":[0.0001752392,0.0001137883,0.00008253381,0.000388874,0.00006892048,0.000008059446,0.00008540797,3.40748e-7,0.01917434,0.0001583828,0.9795569,0.0001872666],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009341777,0.9982952,0.00003102125,0.00003903552,0.0000884511,0.0004161028,0.00005883773,0.000006554804,0.0001306122],"genre_scores_gemma":[0.002303017,0.9969258,0.0001943899,0.00003472407,0.00015898,0.00003297391,0.00007144085,0.00005051333,0.0002281382],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.974757,"threshold_uncertainty_score":0.7800419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009168342621565725,"score_gpt":0.2688038871397047,"score_spread":0.2596355445181389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}