{"id":"W3112545822","doi":"10.1002/stem.3319","title":"CCAAT/enhancer-binding protein beta promotes muscle stem cell quiescence through regulation of quiescence-associated genes","year":2020,"lang":"en","type":"article","venue":"Stem Cells","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Ottawa","funders":"National Institutes of Health; Canadian Institutes of Health Research; King Saud University","keywords":"Biology; Cell biology; Stem cell; Downregulation and upregulation; Mitosis; Progenitor cell; Myocyte; Ccaat-enhancer-binding proteins; Cellular differentiation; Cell cycle; Transcription factor; Skeletal muscle; Cell; Molecular biology; Nuclear protein; Endocrinology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008796422,0.0002820091,0.0001687097,0.000260349,0.0001372631,0.0002126924,0.000117167,0.00009270252,0.001114613],"category_scores_gemma":[0.00009206875,0.0001105549,0.0001350836,0.0001135954,0.0003115596,0.00009359057,0.0001981969,0.0003328428,0.0003073376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002219526,"about_ca_system_score_gemma":0.0002674219,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008622211,"about_ca_topic_score_gemma":0.001484077,"domain_scores_codex":[0.9999275,0.00001051691,0.000003587779,0.0000158127,0.00002022348,0.0000222485],"domain_scores_gemma":[0.9999084,0.00001255233,0.00002579971,0.000006499906,0.00001385807,0.00003292803],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003329091,0.000007990291,0.0001687136,0.0000154885,0.000001684862,0.00002348842,0.000007459108,0.00001292648,0.9989957,0.00007006137,0.00003111316,0.0006319906],"study_design_scores_gemma":[0.00002500953,0.0002173441,0.02782037,0.00001378535,0.00001340648,0.0002690676,0.00003798525,0.0008351579,0.9667905,0.0001321686,0.003840683,0.00000458037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868501,0.004101696,0.003765965,0.000165889,0.00003562111,0.00002698448,0.0003077779,0.000240673,0.004505328],"genre_scores_gemma":[0.9934856,0.001488329,0.001333192,0.00006519514,0.00002074914,0.00003594095,0.0003386587,0.00004222599,0.003190256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001114613,"threshold_uncertainty_score":0.003728747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01785595172843657,"score_gpt":0.2254359279956124,"score_spread":0.2075799762671758,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}