{"id":"W3112545822","doi":"10.1002/stem.3319","title":"CCAAT/enhancer-binding protein beta promotes muscle stem cell quiescence through regulation of quiescence-associated genes","year":2020,"lang":"en","type":"article","venue":"Stem Cells","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Ottawa","funders":"National Institutes of Health; Canadian Institutes of Health Research; King Saud University","keywords":"Biology; Cell biology; Stem cell; Downregulation and upregulation; Mitosis; Progenitor cell; Myocyte; Ccaat-enhancer-binding proteins; Cellular differentiation; Cell cycle; Transcription factor; Skeletal muscle; Cell; Molecular biology; Nuclear protein; Endocrinology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001202381,0.0002099735,0.0002633894,0.0000188974,0.0001104529,0.00001439561,0.000263575,0.0002276212,0.0000409202],"category_scores_gemma":[0.000007641441,0.000208697,0.0001170844,0.0001827065,0.000134051,0.00001535012,0.0001275014,0.00009991692,0.00002740822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001498274,"about_ca_system_score_gemma":0.00008655916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002628159,"about_ca_topic_score_gemma":0.00001143413,"domain_scores_codex":[0.9985722,0.0001373326,0.0003382296,0.000484938,0.0001627025,0.000304578],"domain_scores_gemma":[0.9992189,0.00001589034,0.0002973832,0.0002911691,0.0001048225,0.0000717955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008767859,0.00009157753,0.0002366211,0.0001894677,0.00003252949,6.118404e-7,0.000453308,0.00008181524,0.9968821,0.00004009525,0.0003548408,0.001549401],"study_design_scores_gemma":[0.0005000243,0.0004022658,0.0003583354,0.00005582792,0.00002049778,1.730138e-7,0.0005815331,0.00009471893,0.9969601,0.00004251363,0.0007540641,0.0002299272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969902,0.0007625009,0.0003946249,0.0001695455,0.000110231,0.0005246444,0.0000389406,0.00003143914,0.0009778951],"genre_scores_gemma":[0.9985877,0.0001158022,0.0002634827,0.00003643915,0.00008047558,0.00003058473,0.00006890023,0.00002622688,0.0007903497],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00159756,"threshold_uncertainty_score":0.8510417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01785595172843657,"score_gpt":0.2254359279956124,"score_spread":0.2075799762671758,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}