{"id":"W3112608737","doi":"10.2147/dmso.s275080","title":"<p>The Challenges of Identifying Environmental Determinants of Type 1 Diabetes: In Search of the Holy Grail</p>","year":2020,"lang":"en","type":"review","venue":"Diabetes Metabolic Syndrome and Obesity","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Observational study; Type 2 diabetes; Disease; Genetic predisposition; Medicine; Diabetes mellitus; Etiology; Type 1 diabetes; Obesity; Environmental health; Bioinformatics; Intensive care medicine; Biology; Internal medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001093104,0.000663563,0.001149354,0.001952016,0.0003677629,0.001461077,0.0009695053,0.00155339,0.00303712],"category_scores_gemma":[0.002636449,0.0001908741,0.0004621796,0.00242642,0.001019289,0.002837485,0.0008810469,0.003903965,0.002729714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007637991,"about_ca_system_score_gemma":0.001759086,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00129694,"about_ca_topic_score_gemma":0.001636893,"domain_scores_codex":[0.9995533,0.0001177952,0.00006203893,0.00007032533,0.0001683626,0.00002819226],"domain_scores_gemma":[0.9982451,0.001038066,0.0001394717,0.00005273355,0.0004039027,0.0001207541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005052238,0.00003786218,0.0003448547,0.01056355,0.00006396429,0.000204034,0.00007675531,0.0001392773,0.0004679942,0.005075602,0.09348007,0.8894956],"study_design_scores_gemma":[0.000007323643,0.00005428114,0.001304411,0.006866551,0.00005871055,0.001596524,0.0001450782,0.00007107073,0.0001630479,0.0062999,0.9834119,0.00002111281],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004971925,0.9948259,0.0001394222,0.003084157,0.001086558,0.000002221288,0.00001190936,0.00000951689,0.0007905092],"genre_scores_gemma":[0.0004384067,0.9963682,0.0002475646,0.001034184,0.001280316,0.000004540535,0.00001919077,0.000003190747,0.0006044948],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00303712,"threshold_uncertainty_score":0.01016021,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02068609809900345,"score_gpt":0.2599006314087676,"score_spread":0.2392145333097641,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}