{"id":"W3112691602","doi":"10.1111/cts.12943","title":"Tyrosine Kinase Inhibitors Reduce Glucose Uptake by Binding to an Exofacial Site on hGLUT‐1: Influence on <sup>18</sup>F‐FDG PET Uptake","year":2020,"lang":"en","type":"article","venue":"Clinical and Translational Science","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Cancer Foundation","keywords":"Glucose uptake; Glucose transporter; Tyrosine kinase; Gefitinib; Chemistry; Medicine; Pharmacology; Cancer research; Internal medicine; Cancer; Insulin; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003644406,0.0001830043,0.0002498493,0.00008833524,0.000376018,0.00007706534,0.000137094,0.00005902208,0.0001178968],"category_scores_gemma":[0.0003319755,0.0001436159,0.00008097825,0.0006714914,0.0004650132,0.0003108704,0.00002191527,0.0002380407,0.00009095207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003226304,"about_ca_system_score_gemma":0.0003175903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002864873,"about_ca_topic_score_gemma":0.000007949215,"domain_scores_codex":[0.9978386,0.00003212738,0.0004796251,0.0007316294,0.0006247109,0.0002933229],"domain_scores_gemma":[0.9986456,0.0001520437,0.00006368411,0.0001710512,0.0001190693,0.0008485222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.006889586,0.00578137,0.3580146,0.0001723937,0.0002383117,0.0004409056,0.01062311,0.0143922,0.1204165,0.01180173,0.006959776,0.4642695],"study_design_scores_gemma":[0.006154513,0.005240405,0.9346765,0.0003182514,0.0002076383,0.00002428714,0.0001901904,0.006833383,0.004494887,0.0004226598,0.04089285,0.000544379],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9828215,0.00006942631,0.00006474063,0.01534016,0.0001213222,0.0004438682,0.0002314007,0.00005282517,0.0008547214],"genre_scores_gemma":[0.9936812,0.00003282762,0.00110439,0.004625604,0.0003158413,0.00002060948,0.0000902869,0.00001244094,0.0001167991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5766619,"threshold_uncertainty_score":0.5856488,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05706567021462722,"score_gpt":0.3897668866679653,"score_spread":0.3327012164533381,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}