{"id":"W3112835911","doi":"10.3390/vaccines9010033","title":"Modulation of Antigen Display on PapMV Nanoparticles Influences Its Immunogenicity","year":2021,"lang":"en","type":"article","venue":"Vaccines","topic":"Biochemical and Structural Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Immunogenicity; Antigen; Epitope; Peptide; Immune system; CTL*; Virology; Biology; Virus; Cytotoxic T cell; Chemistry; CD8; Immunology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000266261,0.00007432579,0.00008403478,0.00001083159,0.00003398545,0.00000957643,0.00006408396,0.00007116795,0.00002511569],"category_scores_gemma":[0.00005869956,0.00005923519,0.00004408468,0.00008324687,0.0000103246,0.000005129111,0.00004040822,0.00002486827,0.000002730265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002445333,"about_ca_system_score_gemma":0.00001568875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004432463,"about_ca_topic_score_gemma":0.000004512805,"domain_scores_codex":[0.9995168,0.0000230637,0.0001463294,0.0001623345,0.0000660558,0.00008538333],"domain_scores_gemma":[0.9996661,0.000005634272,0.00006025063,0.0001350032,0.0001095062,0.00002350339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007776234,0.00001979942,0.01310019,0.00001359665,0.00001744745,4.893948e-7,0.00001305756,0.00005428331,0.9854679,0.00006994821,0.00003307347,0.001132457],"study_design_scores_gemma":[0.0001171757,0.00004934669,0.2713922,0.000008376363,0.000003914923,0.000002386191,0.000005993852,0.00008319047,0.7278445,0.00005264658,0.0003840854,0.00005618489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991783,0.0004299307,0.00002254492,0.0001783692,0.00007675913,0.00004288122,0.00001855135,0.000005969306,0.00004662694],"genre_scores_gemma":[0.9992641,0.000203039,0.00006909004,0.00009800484,0.00009179977,0.000002575275,0.0001705222,0.000005136428,0.00009571337],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.258292,"threshold_uncertainty_score":0.2415541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01038953187353029,"score_gpt":0.242160043737749,"score_spread":0.2317705118642187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}