{"id":"W3112835911","doi":"10.3390/vaccines9010033","title":"Modulation of Antigen Display on PapMV Nanoparticles Influences Its Immunogenicity","year":2021,"lang":"en","type":"article","venue":"Vaccines","topic":"Biochemical and Structural Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Immunogenicity; Antigen; Epitope; Peptide; Immune system; CTL*; Virology; Biology; Virus; Cytotoxic T cell; Chemistry; CD8; Immunology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001272104,0.0002290703,0.0001362124,0.00007134033,0.00007232706,0.0002363705,0.0001289876,0.0002300799,0.0008042093],"category_scores_gemma":[0.0002409588,0.0000939555,0.0001230678,0.00006597327,0.0001477129,0.0001783509,0.0001485701,0.000268048,0.0002175079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001661123,"about_ca_system_score_gemma":0.0000740997,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001652466,"about_ca_topic_score_gemma":0.00018521,"domain_scores_codex":[0.9998822,0.00002217932,0.000007100643,0.00002666051,0.00002738044,0.00003437272],"domain_scores_gemma":[0.9998863,0.00004119891,0.00002524432,0.000007605561,0.00002402195,0.00001559802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005586259,0.00001391591,0.00007063243,0.00002281105,0.000002143534,0.00001252191,0.000006688175,0.00008669562,0.9992187,0.00001984879,0.00001087139,0.0004793027],"study_design_scores_gemma":[0.000005318987,0.0002163336,0.000720256,0.000003581066,0.000007622368,0.00003003092,0.000008246525,0.000884209,0.9977238,0.0000120757,0.0003860875,0.000002442318],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979954,0.0003548938,0.0008691798,0.00001997354,0.00001237456,0.000009314637,0.00002597759,0.00001401123,0.0006989411],"genre_scores_gemma":[0.9983431,0.0002328314,0.0008663151,0.00002661124,0.000005826907,0.00001491671,0.00004434068,0.00001057755,0.0004554436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008042093,"threshold_uncertainty_score":0.002690375,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01038953187353029,"score_gpt":0.242160043737749,"score_spread":0.2317705118642187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}