{"id":"W3112934918","doi":"10.1016/j.jaci.2020.11.044","title":"Shared DNA methylation signatures in childhood allergy: The MeDALL study","year":2020,"lang":"en","type":"review","venue":"Journal of Allergy and Clinical Immunology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean; Université du Québec à Chicoutimi","funders":"FP7 Health; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; National Institute of Environmental Health Sciences; European Commission","keywords":"DNA methylation; Allergy; CpG site; Asthma; Epigenetics; Methylation; Immunology; Differentially methylated regions; Medicine; Biology; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001166597,0.0005023365,0.0006335636,0.0006883338,0.0007004925,0.0006315546,0.0005556589,0.0006176417,0.001826251],"category_scores_gemma":[0.001785882,0.0004462456,0.0009221543,0.001123317,0.0004330513,0.0003354003,0.0008903043,0.0006119577,0.000157005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003302365,"about_ca_system_score_gemma":0.0002791814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007668051,"about_ca_topic_score_gemma":0.01211432,"domain_scores_codex":[0.9987639,0.0004110527,0.00007399424,0.0004846697,0.0001279334,0.000138421],"domain_scores_gemma":[0.9986749,0.0002220674,0.0005363676,0.0003152322,0.00007751457,0.0001739853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001133118,0.00003229476,0.9907157,0.00006870664,0.001204317,0.0002550589,0.0002397734,0.0001078402,0.002845353,0.0001650214,0.0004561433,0.002776625],"study_design_scores_gemma":[0.00006648558,0.0001037491,0.9968513,0.00002375321,0.0006983752,0.0005095077,0.0001406381,0.0002198367,0.0004062061,0.00008503448,0.0008872352,0.000007918791],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.996641,0.001250105,0.0003941073,0.0001316781,0.000009503879,0.000009656048,0.001140906,0.000009019932,0.0004140656],"genre_scores_gemma":[0.9988047,0.0002500852,0.0002633168,0.00005046098,0.0000136126,0.00001079995,0.0004663341,0.000007094763,0.0001337127],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.007668051,"threshold_uncertainty_score":0.01524681,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03798953010827278,"score_gpt":0.363111678651314,"score_spread":0.3251221485430412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}