{"id":"W3112945290","doi":"10.1136/ijgc-2020-esgo.71","title":"385 Safety and antitumor activity of dostarlimab in patients (PTS) with advanced or recurrent DNA mismatch repair deficient (DMMR) or proficient (MMRP) endometrial cancer (EC): results from the garnet study","year":2020,"lang":"en","type":"article","venue":"International Journal of Gynecological Cancer","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Discontinuation; Internal medicine; Endometrial cancer; Oncology; Cohort; Regimen; Tolerability; Cancer; Population; Immunohistochemistry; Surgery; Adverse effect","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006684554,0.0003723027,0.0009620434,0.0002371057,0.0001388489,0.0004958355,0.0002591625,0.0004669849,0.001122385],"category_scores_gemma":[0.000567528,0.0001660663,0.0006172839,0.000260418,0.0003619838,0.0003851097,0.0001800692,0.0006845685,0.0003617188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000463173,"about_ca_system_score_gemma":0.0003254793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004050163,"about_ca_topic_score_gemma":0.0008100704,"domain_scores_codex":[0.9997107,0.0001383663,0.00001691647,0.00004509165,0.00004322792,0.00004557295],"domain_scores_gemma":[0.9997018,0.00009239619,0.00008209272,0.00003069995,0.00001489786,0.0000780371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4725502,0.005793071,0.2275988,0.0007419456,0.002357926,0.0006875802,0.0003939241,0.004647456,0.07480801,0.0004032596,0.001716718,0.2083012],"study_design_scores_gemma":[0.06202715,0.3427143,0.5567474,0.0001294501,0.003189001,0.001634477,0.0002725444,0.004476877,0.01747965,0.0007463938,0.01050261,0.0000801791],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975824,0.001393826,0.00006505304,0.00006564835,0.00001023516,0.00002579855,0.0002568781,0.00001042864,0.0005897484],"genre_scores_gemma":[0.9978114,0.0006230387,0.00009709015,0.0001348881,0.00002696207,0.00003306216,0.0006905084,0.000006858153,0.0005761965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001122385,"threshold_uncertainty_score":0.003754735,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02474877986844086,"score_gpt":0.2988950487801237,"score_spread":0.2741462689116829,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}