{"id":"W3112974977","doi":"10.1152/ajpendo.00547.2020","title":"Peripheral and central regulation of insulin by the intestine and microbiome","year":2020,"lang":"en","type":"article","venue":"American Journal of Physiology-Endocrinology and Metabolism","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; Diabetes Canada; University of Toronto; McMaster University","funders":"Canadian Institutes of Health Research; University of Toronto; Government of Canada","keywords":"Insulin; Insulin resistance; Glucose homeostasis; Biology; Enteroendocrine cell; Homeostasis; Endocrinology; Internal medicine; Gut flora; Insulin receptor; Microbiome; Endocrine system; Medicine; Immunology; Hormone; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003767765,0.0003477925,0.0005163407,0.0003288842,0.0002781457,0.0008220565,0.0002278112,0.0005312111,0.003549293],"category_scores_gemma":[0.0004044217,0.0002140814,0.0004656061,0.0002190198,0.0004932369,0.0006829935,0.0008950083,0.001010914,0.000620876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003822065,"about_ca_system_score_gemma":0.0003879834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004621974,"about_ca_topic_score_gemma":0.0007638511,"domain_scores_codex":[0.9996626,0.000090341,0.00002154742,0.00009174826,0.00006514793,0.00006853296],"domain_scores_gemma":[0.9997558,0.00002725026,0.00006139394,0.00002720769,0.0000449303,0.0000833997],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002954112,0.0002648782,0.01334635,0.00226288,0.0002992986,0.00096679,0.0002771646,0.0004196814,0.7467374,0.008507375,0.006565901,0.2173982],"study_design_scores_gemma":[0.0006551337,0.004587845,0.4755991,0.001552733,0.0007750299,0.005530251,0.001518012,0.004354588,0.209943,0.02403784,0.2712017,0.0002445876],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5678334,0.3229315,0.04504215,0.01014032,0.002523906,0.0002012384,0.002277229,0.001042497,0.04800774],"genre_scores_gemma":[0.886863,0.07693253,0.01907021,0.002288163,0.0007577963,0.0001789006,0.0007223844,0.0001096931,0.01307734],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003549293,"threshold_uncertainty_score":0.0118736,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00627518970628977,"score_gpt":0.2285446188157951,"score_spread":0.2222694291095054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}