{"id":"W3113002109","doi":"10.1093/neuonc/noaa215.190","title":"CTNI-23. IDH1/2wt ANAPLASTIC GLIOMAS OF THE EORTC RANDOMIZED PHASE III INTERGROUP CATNON TRIAL: OVERALL SURVIVAL RELATED TO TREATMENT, MGMT STATUS AND MOLECULAR FEATURES OF GLIOBLASTOMA","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"IDH1; Anaplastic astrocytoma; Internal medicine; Glioma; Medicine; Oncology; Astrocytoma; Adjuvant therapy; Isocitrate dehydrogenase; Methylation; Cancer research; Biology; Chemotherapy; Mutation; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001384294,0.000882569,0.001465835,0.000197455,0.0002627231,0.0009389522,0.0005357123,0.0006835776,0.002035333],"category_scores_gemma":[0.0009816716,0.0002370114,0.0009536967,0.0003131724,0.0005626678,0.000443954,0.0002409067,0.001520262,0.000244082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009175836,"about_ca_system_score_gemma":0.0009979174,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001510929,"about_ca_topic_score_gemma":0.004930711,"domain_scores_codex":[0.9994684,0.0003509414,0.00002324133,0.00007425547,0.00003335861,0.00004988572],"domain_scores_gemma":[0.9994509,0.0001022194,0.0001357815,0.00004871207,0.00003320902,0.0002291445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9648663,0.001815424,0.00635768,0.000477476,0.001897962,0.00006818092,0.00003782029,0.001019109,0.004023411,0.0002682518,0.002433884,0.01673444],"study_design_scores_gemma":[0.8311023,0.1224042,0.03163002,0.0001537441,0.003755719,0.0002450435,0.00008768825,0.002647805,0.002019084,0.001086861,0.004810356,0.00005711651],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882698,0.005808785,0.0003334497,0.0007073707,0.0003113852,0.000883727,0.00140568,0.00004218214,0.00223761],"genre_scores_gemma":[0.9900846,0.001815859,0.000562732,0.0007129172,0.000214029,0.001478382,0.002644771,0.00002194357,0.002464713],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002035333,"threshold_uncertainty_score":0.007320881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01517410566992267,"score_gpt":0.3051012183696928,"score_spread":0.2899271126997701,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}