{"id":"W3113178872","doi":"10.3390/pathogens9121027","title":"Mechanisms of Dysregulated Humoral and Cellular Immunity by SARS-CoV-2","year":2020,"lang":"en","type":"review","venue":"Pathogens","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Ontario Ministry of Research and Innovation; Canadian Institutes of Health Research","keywords":"Immune system; Immunology; Acquired immune system; Immunity; Virology; Humoral immunity; Antibody; Disease; Virus; Cellular immunity; Pathogenesis; T cell; Pandemic; Biology; Medicine; Coronavirus disease 2019 (COVID-19); Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035457,0.0005487158,0.0007935492,0.001204631,0.0001681383,0.0007120072,0.0004641259,0.000709407,0.002668812],"category_scores_gemma":[0.0004894632,0.0001559815,0.0003924935,0.0008802363,0.0002485543,0.0007818178,0.0004526679,0.0009933775,0.001090609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003709122,"about_ca_system_score_gemma":0.0007834836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006014454,"about_ca_topic_score_gemma":0.000903687,"domain_scores_codex":[0.9998958,0.00002006077,0.00001865166,0.00001835619,0.00003278824,0.00001437018],"domain_scores_gemma":[0.99985,0.00006024512,0.00002589188,0.000003923091,0.00004434552,0.00001558562],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001307157,0.00006120694,0.0002980419,0.0226681,0.0001023694,0.0002031217,0.00007973577,0.0003330877,0.002904172,0.002957014,0.02914901,0.9411134],"study_design_scores_gemma":[0.00002584237,0.0001574397,0.001461303,0.004921206,0.0001560382,0.001313964,0.00007373759,0.00009575481,0.0007136891,0.001812023,0.9892509,0.00001820086],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002035089,0.9985066,0.00007602534,0.0002634784,0.0001659477,0.000004224015,0.00002135202,0.000007155517,0.0007517173],"genre_scores_gemma":[0.000780773,0.9984983,0.00007936744,0.0001501216,0.0001006717,0.000005616073,0.00002771315,7.235852e-7,0.0003567339],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002668812,"threshold_uncertainty_score":0.008928001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07856635899320365,"score_gpt":0.3622754733689895,"score_spread":0.2837091143757858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}