{"id":"W3113178872","doi":"10.3390/pathogens9121027","title":"Mechanisms of Dysregulated Humoral and Cellular Immunity by SARS-CoV-2","year":2020,"lang":"en","type":"review","venue":"Pathogens","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Ontario Ministry of Research and Innovation; Canadian Institutes of Health Research","keywords":"Immune system; Immunology; Acquired immune system; Immunity; Virology; Humoral immunity; Antibody; Disease; Virus; Cellular immunity; Pathogenesis; T cell; Pandemic; Biology; Medicine; Coronavirus disease 2019 (COVID-19); Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005389363,0.0005471247,0.002517168,0.0002555641,0.00008900981,0.00003552997,0.0004285161,0.0005279707,0.00001826885],"category_scores_gemma":[0.0002001675,0.0004521579,0.0005675072,0.0006880568,0.0001842315,0.00003789399,0.0003776192,0.0008483053,0.0000960211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001222024,"about_ca_system_score_gemma":0.0005027093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000986403,"about_ca_topic_score_gemma":0.000003639188,"domain_scores_codex":[0.9971092,0.0003363639,0.0007604808,0.0006145703,0.0006873212,0.000492067],"domain_scores_gemma":[0.99854,0.0001362665,0.000306477,0.0007847816,0.0001481337,0.00008435355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006849918,0.0002313779,0.00002606512,0.02111969,0.0005274882,0.0006290984,0.000131838,1.749506e-9,0.6545196,0.0002206667,0.0007811327,0.3217446],"study_design_scores_gemma":[0.0005553759,0.0003261518,0.000002801762,0.002769019,0.001107297,0.0001289071,0.00002464977,0.00001550798,0.1335907,0.0001676593,0.8609767,0.0003352796],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00345212,0.9937317,0.0002828591,0.0000332314,0.0001028055,0.001221064,0.0003961005,0.00009062346,0.0006895065],"genre_scores_gemma":[0.001731508,0.9929065,0.0004979282,0.003947753,0.0001422399,0.0001184959,0.0003708041,0.0002217489,0.00006308792],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8601956,"threshold_uncertainty_score":0.999793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07856635899320365,"score_gpt":0.3622754733689895,"score_spread":0.2837091143757858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}