{"id":"W3113203663","doi":"10.1101/2020.12.16.423062","title":"Oncolytic virus treatment differentially affects the CD56 <sup>dim</sup> and CD56 <sup>bright</sup> NK cell subsets <i>in vivo</i> and regulates a spectrum of human NK cell activity","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research; Oncolytics Biotech (Canada)","funders":"Oncolytics Biotech; Cancer Research UK","keywords":"Oncolytic virus; Biology; Natural killer cell; Interleukin 21; Interferon; Interleukin 12; Cell; Virus; Virology; T cell; Immune system; Immunology; Cytotoxic T cell; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009199389,0.0002441094,0.0001810435,0.0001402955,0.00008128079,0.0003247072,0.00008971347,0.0001856391,0.001603788],"category_scores_gemma":[0.00006070209,0.0001034462,0.0001540355,0.00007987179,0.0002137978,0.0001460003,0.0001161146,0.000530835,0.0003450599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001546504,"about_ca_system_score_gemma":0.00009697068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001901854,"about_ca_topic_score_gemma":0.0002380825,"domain_scores_codex":[0.9998512,0.00002008739,0.0000187431,0.00003765287,0.00002484875,0.00004745686],"domain_scores_gemma":[0.9999378,0.00001229414,0.00001752559,0.000008466614,0.000004736689,0.00001919644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001509418,0.00001493585,0.0001269454,0.000009749441,0.000001652798,0.000008637683,0.000005089671,0.00001348755,0.9993269,0.00002768036,0.00001183477,0.0003020467],"study_design_scores_gemma":[0.000009104357,0.000272688,0.004667285,0.000002140375,0.000008874249,0.00009408921,0.00001931396,0.0002355677,0.9938182,0.00002059277,0.0008501196,0.000001990239],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967373,0.0005311322,0.0009927338,0.00004392611,0.00001877209,0.00001749564,0.000439902,0.000034157,0.001184609],"genre_scores_gemma":[0.9952278,0.0003133001,0.0008883065,0.00004156008,0.000007028329,0.00003932567,0.0006246513,0.00002205152,0.00283604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001603788,"threshold_uncertainty_score":0.005365193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01078327833727268,"score_gpt":0.2059946436361827,"score_spread":0.19521136529891,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}