{"id":"W3113218350","doi":"10.1002/alz.040422","title":"Chronic exposure to mild therapeutic hypothermia prevents cognitive deterioration and neurodegeneration in a rat model of AD‐like pathology","year":2020,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Neurodegeneration; Neuroscience; Genetically modified mouse; Epigenetics; Neuroplasticity; Biology; Cognitive decline; Demethylase; Transgene; Endocrinology; Synaptic plasticity; Gene expression; Cell biology; Internal medicine; Medicine; Gene; Genetics; Disease; Dementia; Receptor","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002214101,0.001313619,0.0008919036,0.001084264,0.0003249441,0.0002526951,0.0004534132,0.0004980846,0.001400166],"category_scores_gemma":[0.0001028197,0.0003450454,0.0005761698,0.0002993477,0.0006457918,0.0003723625,0.0003007703,0.001264068,0.0003983144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004445804,"about_ca_system_score_gemma":0.0004479901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001528826,"about_ca_topic_score_gemma":0.002634548,"domain_scores_codex":[0.9998086,0.00001597298,0.00002211445,0.00005454501,0.00003752905,0.00006113397],"domain_scores_gemma":[0.9997155,0.000008878208,0.0001190735,0.00003923575,0.00002857687,0.00008874311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002604268,0.00104323,0.0009276634,0.000112229,0.00004358569,0.0001400782,0.00005502328,0.00008939477,0.9922392,0.00008568764,0.0001735265,0.00248607],"study_design_scores_gemma":[0.0002910472,0.01704686,0.02775504,0.00005701479,0.00027606,0.000729694,0.0001872126,0.0009382605,0.9497951,0.0001990792,0.002681792,0.00004281706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994843,0.001490049,0.00181229,0.00009281341,0.00008160853,0.0001128949,0.0006965114,0.0002367415,0.00063418],"genre_scores_gemma":[0.9890321,0.001999415,0.003366838,0.00008537721,0.00004027649,0.000445822,0.001099038,0.00003272086,0.003898385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001528826,"threshold_uncertainty_score":0.004684031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05123973352980161,"score_gpt":0.2878849592752231,"score_spread":0.2366452257454215,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}