{"id":"W3113309259","doi":"10.1182/blood-2021-147101","title":"Part 1 Results of a Dose-Finding Study of Belantamab Mafodotin in Combination with Pomalidomide and Dexamethasone for the Treatment of Relapsed/Refractory Multiple Myeloma (RRMM)","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; Juravinski Cancer Centre; Queen Elizabeth II Health Sciences Centre; University of Alberta; London Health Sciences Centre; Western University; CancerCare Manitoba; Vancouver General Hospital; Ottawa Hospital; Princess Margaret Cancer Centre","funders":"","keywords":"Pomalidomide; Lenalidomide; Medicine; Multiple myeloma; Dosing; Dexamethasone; Internal medicine; Refractory (planetary science); Pharmacology; Adverse effect; Oncology; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002038404,0.001111703,0.001951757,0.0007396159,0.0005374006,0.001038922,0.001105912,0.001255363,0.003742505],"category_scores_gemma":[0.00152363,0.0005965934,0.001826669,0.0004289837,0.000946396,0.0006397326,0.0003517839,0.003104168,0.0008486749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001467886,"about_ca_system_score_gemma":0.00119353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001194544,"about_ca_topic_score_gemma":0.001845217,"domain_scores_codex":[0.9990882,0.0004388887,0.00007137504,0.0001483411,0.0001398471,0.0001134874],"domain_scores_gemma":[0.9988621,0.0002348993,0.000211326,0.000152512,0.00008795494,0.0004511548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5478653,0.1660246,0.01138339,0.0008248047,0.002825151,0.001199172,0.0007099697,0.005705608,0.1612686,0.0003873465,0.004420782,0.09738526],"study_design_scores_gemma":[0.1274415,0.8115237,0.03275792,0.00003767894,0.001060875,0.0007785487,0.00006751992,0.00103816,0.0200349,0.0002088312,0.004994696,0.00005553068],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922205,0.001378092,0.0007278416,0.00027222,0.00005977816,0.002178455,0.001617778,0.00006785365,0.001477482],"genre_scores_gemma":[0.9907643,0.0008396818,0.001739453,0.0005960397,0.0001214022,0.001247678,0.002590158,0.00003825131,0.002063008],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003742505,"threshold_uncertainty_score":0.01251996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05008346032906371,"score_gpt":0.3130110165952611,"score_spread":0.2629275562661975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}