{"id":"W3113322471","doi":"10.3390/pharmaceutics12121232","title":"Biodegradable Nanoparticle for Cornea Drug Delivery: Focus Review","year":2020,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Corneal Surgery and Treatments","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Cornea; Drug delivery; Nanocarriers; Drug; Niosome; Targeted drug delivery; Self-healing hydrogels; Nanotechnology; Corneal disease; Corneal Diseases; Biomedical engineering; Pharmacology; Medicine; Materials science; Ophthalmology; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003660453,0.001000583,0.000955548,0.002656087,0.0002766557,0.0008224989,0.0005182091,0.0007937086,0.004952827],"category_scores_gemma":[0.000395937,0.0003293093,0.0005464971,0.002651622,0.0002423463,0.001023899,0.0005101283,0.001050555,0.002255567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004093731,"about_ca_system_score_gemma":0.0009289515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001174305,"about_ca_topic_score_gemma":0.001726552,"domain_scores_codex":[0.9998615,0.00001544218,0.00001881061,0.00003150833,0.00005323178,0.00001944249],"domain_scores_gemma":[0.9998201,0.00007953854,0.00003355569,0.0000051567,0.00004686106,0.00001481837],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004829212,0.0001263405,0.0001411013,0.03558323,0.00009993447,0.0002471916,0.00009272489,0.0005527039,0.007642575,0.004249022,0.02989833,0.9213187],"study_design_scores_gemma":[0.00001034786,0.00010896,0.0004509956,0.003137383,0.0001208471,0.0009500061,0.00003813775,0.000113566,0.001729973,0.0008828688,0.9924384,0.00001855745],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002302136,0.9977319,0.0002218944,0.0001172112,0.0002015346,0.000008229293,0.00002801346,0.00001041251,0.001450644],"genre_scores_gemma":[0.0009514954,0.9975302,0.000284975,0.0001177732,0.00009966466,0.000009786273,0.00003824633,0.000002471513,0.0009654888],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004952827,"threshold_uncertainty_score":0.01656884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1742019690636882,"score_gpt":0.4215457363808794,"score_spread":0.2473437673171912,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}