{"id":"W3113322471","doi":"10.3390/pharmaceutics12121232","title":"Biodegradable Nanoparticle for Cornea Drug Delivery: Focus Review","year":2020,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Corneal Surgery and Treatments","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Cornea; Drug delivery; Nanocarriers; Drug; Niosome; Targeted drug delivery; Self-healing hydrogels; Nanotechnology; Corneal disease; Corneal Diseases; Biomedical engineering; Pharmacology; Medicine; Materials science; Ophthalmology; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002706592,0.0004802616,0.002274203,0.00006006139,0.00009828493,0.00002025547,0.0001548364,0.000106197,0.0002218483],"category_scores_gemma":[0.0001062056,0.0003625416,0.0009249747,0.0004666832,0.0000406254,0.00005265593,0.0000835989,0.0003331163,0.0005811109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002028463,"about_ca_system_score_gemma":0.0004832432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001101696,"about_ca_topic_score_gemma":0.00000186015,"domain_scores_codex":[0.998003,0.0001028133,0.0006742473,0.0004867014,0.0002358634,0.000497381],"domain_scores_gemma":[0.9984281,0.0003368394,0.0002831031,0.0003651011,0.0001045839,0.000482285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004122773,0.0001807002,0.0000152282,0.0776547,0.0005547379,0.0001575542,0.000007693892,1.077008e-8,0.000002018566,0.00001295152,0.0225399,0.8988333],"study_design_scores_gemma":[0.0007445249,0.00007402639,2.213276e-7,0.03023619,0.01332738,0.000122708,0.000001437097,0.00004809282,0.0002599483,0.00001816979,0.9548766,0.0002907197],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000004905183,0.9947146,0.00000884573,0.0008776726,0.0003677938,0.003248739,0.000313817,0.0001284217,0.0003352691],"genre_scores_gemma":[0.0000285695,0.9961848,0.0002377094,0.001550828,0.000233368,0.0004662581,0.0003475788,0.00009236146,0.0008585501],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9323367,"threshold_uncertainty_score":0.9998826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1742019690636882,"score_gpt":0.4215457363808794,"score_spread":0.2473437673171912,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}