{"id":"W3113573257","doi":"10.1111/petr.13959","title":"Age and sex determine conversion from immediate‐release to extended‐release tacrolimus in a multi‐center cohort of Canadian pediatric renal transplant recipients","year":2020,"lang":"en","type":"article","venue":"Pediatric Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Research Manitoba; McGill University; The Metabolomics Innovation Centre; McGill University Health Centre; Montreal Children's Hospital; University of Manitoba; George & Fay Yee Centre for Healthcare Innovation; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Tacrolimus; Proportional hazards model; Cohort; Internal medicine; Observational study; Prospective cohort study; Transplantation; Cohort study; Renal transplant; Trough level","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005112991,0.0002855114,0.0002861043,0.0004572157,0.0007658285,0.0006597376,0.0005523204,0.0003503441,0.001526727],"category_scores_gemma":[0.001666647,0.0002123898,0.0006416772,0.0008928146,0.000290308,0.0002143052,0.0003257354,0.0006418139,0.0001168498],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002573393,"about_ca_system_score_gemma":0.00407169,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.6497362,"about_ca_topic_score_gemma":0.6583394,"domain_scores_codex":[0.9995406,0.00004526319,0.00002254471,0.00008665997,0.0001431027,0.0001618819],"domain_scores_gemma":[0.9988569,0.0001235738,0.000519351,0.00007269991,0.0001883483,0.0002390579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00003512081,0.000009629041,0.998881,0.000002478696,0.00001586595,0.00002566057,0.00005001265,0.00001959921,0.00005946546,0.000007162434,0.00005735991,0.0008364763],"study_design_scores_gemma":[0.000002343198,0.00002219677,0.999494,0.000003564353,0.00001611811,0.0001002865,0.00008822158,0.0001214007,0.00003091304,0.000004854455,0.0001139234,0.000002275827],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992946,0.0001643399,0.00003321837,0.00004133731,0.000002852187,0.000003765967,0.0002010881,0.000002279653,0.000256419],"genre_scores_gemma":[0.9994149,0.0001143305,0.00005485289,0.00002314284,0.000003290056,0.000002892459,0.0002531913,0.000001662307,0.0001316141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3502638,"threshold_uncertainty_score":0.7046531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02154400173402372,"score_gpt":0.2553418285274406,"score_spread":0.2337978267934169,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}