{"id":"W3113589313","doi":"10.1101/2020.12.23.424179","title":"<i>On-chip</i> perivascular niche with patient-derived glioma cells","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"3D Printing in Biomedical Research","field":"Engineering","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Engineering and Physical Sciences Research Council; National Institute for Health and Care Research; Cancer Research UK","keywords":"Angiogenesis; Biology; Pericyte; Endothelial stem cell; Matrigel; Glioma; Cancer research; Cell biology; Stem cell; Pathology; Cancer stem cell; Medicine; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003164822,0.0003903655,0.0003073423,0.0001777138,0.0001481991,0.0003047007,0.0003679235,0.0003906035,0.001409036],"category_scores_gemma":[0.0002439484,0.0001647334,0.0003333906,0.0001809047,0.0001336015,0.0001343466,0.0002672198,0.0002455321,0.0005899151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002647642,"about_ca_system_score_gemma":0.0001783987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007442707,"about_ca_topic_score_gemma":0.001236939,"domain_scores_codex":[0.9995124,0.00006421547,0.00003666488,0.0001609181,0.0001353202,0.00009038464],"domain_scores_gemma":[0.9998678,0.00003683654,0.00002257085,0.00002202744,0.00003713912,0.00001354764],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006436089,0.00003976096,0.0005696641,0.00008254084,0.00001487111,0.0000658787,0.00003678778,0.0002114614,0.9953622,0.00008349939,0.0004191144,0.003050031],"study_design_scores_gemma":[0.000007131036,0.0001852168,0.003612997,0.000007239576,0.00001831781,0.0001416213,0.00003059983,0.002130091,0.9894617,0.00002764051,0.004364839,0.00001267419],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9415935,0.002390894,0.04586368,0.0003269216,0.0002657058,0.0002585499,0.0032248,0.0009210713,0.005154795],"genre_scores_gemma":[0.9529127,0.0008831767,0.03866648,0.0003518775,0.00004471436,0.000578176,0.003060998,0.00008582354,0.003415894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001409036,"threshold_uncertainty_score":0.004713655,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01159312914101783,"score_gpt":0.2044804789460941,"score_spread":0.1928873498050763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}