{"id":"W3113611571","doi":"10.2139/ssrn.3684850","title":"HNRNPA2B1 Mediates the Association of Oligomeric Tau with N &lt;sup&gt;6&lt;/sup&gt;-Methyladenosine and Neurodegeneration","year":2020,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Neurodegeneration; Stress granule; Tauopathy; RNA-binding protein; Proteomics; Cell biology; Proteome; Chemistry; Biology; Molecular biology; Biochemistry; RNA; Translation (biology); Messenger RNA; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002561029,0.0003623832,0.0003127568,0.0002287242,0.0002700813,0.0003706333,0.0004020791,0.0003500888,0.002585133],"category_scores_gemma":[0.0002440305,0.0003049152,0.0002665094,0.0001309899,0.0002851406,0.0002730367,0.0003517659,0.0005373931,0.001024004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003396364,"about_ca_system_score_gemma":0.0002014651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001568687,"about_ca_topic_score_gemma":0.003151181,"domain_scores_codex":[0.9998604,0.00002785935,0.000009821847,0.0000410615,0.00002618532,0.00003468006],"domain_scores_gemma":[0.9998259,0.00002253218,0.00006153776,0.00002222864,0.00001674957,0.00005107194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003363584,0.00002684164,0.0005017075,0.00002184669,0.00001102302,0.00007827706,0.00001890444,0.00003497499,0.9979351,0.0001304809,0.00005993896,0.0008446669],"study_design_scores_gemma":[0.00003854686,0.0002642944,0.04836124,0.0000120015,0.00002658776,0.0005956689,0.00009050988,0.001253125,0.9472628,0.0002959819,0.00178887,0.00001045917],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995233,0.001520588,0.001365682,0.0001319379,0.00002880168,0.000008807899,0.0002322878,0.00006671235,0.001412188],"genre_scores_gemma":[0.9940984,0.0005540538,0.0008469148,0.00003994643,0.00001330647,0.00001317982,0.0004651582,0.00002808077,0.003940936],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002585133,"threshold_uncertainty_score":0.008648157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004835138098645942,"score_gpt":0.2056242140750396,"score_spread":0.2007890759763937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}