{"id":"W3113698616","doi":"10.1089/crispr.2020.0049","title":"Heritable Human Genome Editing: The Public Engagement Imperative","year":2020,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Obligation; Genome editing; Warrant; Bioethics; Commission; Political science; Public engagement; Public relations; Genome; Law; Biology; Genetics; Business","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.08474845,0.0008959984,0.001220306,0.0008999277,0.01325268,0.02903496,0.002913038,0.04371633,0.009387312],"category_scores_gemma":[0.08579609,0.0007269796,0.001116413,0.0008820124,0.03657914,0.0255917,0.02721258,0.04954271,0.002837501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006880857,"about_ca_system_score_gemma":0.03106591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001895608,"about_ca_topic_score_gemma":0.001928579,"domain_scores_codex":[0.9357245,0.03548134,0.001677313,0.005564995,0.01439127,0.007160606],"domain_scores_gemma":[0.880271,0.08327302,0.005125783,0.006688323,0.008859937,0.01578185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005326685,0.00009243181,0.0004619621,0.0002056363,0.00003060541,0.0004859326,0.01107307,0.0002147493,0.001152617,0.8165657,0.1346895,0.03497447],"study_design_scores_gemma":[0.00003005454,0.00008325402,0.0003370889,0.0003017693,0.00001851066,0.0003536297,0.005549202,0.0003195372,0.0007651803,0.33004,0.6621267,0.00007507758],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.002324803,0.002605931,0.006842482,0.9594473,0.004272846,0.00004114757,0.00002760253,0.00007340631,0.02436439],"genre_scores_gemma":[0.2206279,0.003963849,0.007312495,0.7313152,0.009384883,0.0002695794,0.0001150406,0.0001687977,0.02684231],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.08474845,"threshold_uncertainty_score":0.448198,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02969435136112262,"score_gpt":0.3177105939838223,"score_spread":0.2880162426226996,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}