{"id":"W3114062763","doi":"10.3390/curroncol28010021","title":"A Rare p.T599dup BRAF Mutant NSCLC in a Non-Smoker","year":2020,"lang":"en","type":"article","venue":"Current Oncology","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Kinase; Cancer research; Mutation; Lung cancer; Targeted therapy; Fibrosarcoma; MAPK/ERK pathway; Mutant; non-small cell lung cancer (NSCLC); Cancer; Oncogene; MEK inhibitor; Oncology; Biology; Internal medicine; Genetics; Gene; Pathology; Cell cycle; A549 cell","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002232505,0.001241464,0.001063753,0.001599055,0.001570419,0.0007839769,0.001013436,0.003776976,0.002397479],"category_scores_gemma":[0.001611106,0.0006739262,0.001129908,0.0007885198,0.001033416,0.001096485,0.0009183174,0.002094344,0.0009448401],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007321038,"about_ca_system_score_gemma":0.0005328656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002635221,"about_ca_topic_score_gemma":0.003789345,"domain_scores_codex":[0.9995665,0.00003025525,0.00005271802,0.0001479432,0.0000866347,0.0001159849],"domain_scores_gemma":[0.9990895,0.00019952,0.0001995051,0.00005800434,0.00006916557,0.0003842871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00002341828,0.00001404199,0.003386836,0.00001431464,0.000003371781,0.9947796,0.00005525408,0.00002431366,0.001016485,0.00004467968,0.0001008877,0.0005368352],"study_design_scores_gemma":[0.000002925408,0.00005575806,0.004526727,0.000006963908,0.000005414252,0.994695,0.00004359297,0.00009950401,0.0003131521,0.00005337965,0.0001920712,0.000005536059],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852328,0.00252371,0.00222621,0.002114937,0.0002924456,0.0001441797,0.0003391414,0.0001845881,0.006942007],"genre_scores_gemma":[0.9962543,0.0007071378,0.000733507,0.0004960332,0.0002345492,0.00001560112,0.00009444604,0.00002646213,0.00143796],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003776976,"threshold_uncertainty_score":0.008020341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0582683928221223,"score_gpt":0.3323510831691569,"score_spread":0.2740826903470346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}