{"id":"W3114097737","doi":"10.1080/19490976.2020.1862027","title":"Changes in IgA-targeted microbiota following fecal transplantation for recurrent <i>Clostridioides difficile</i> infection","year":2020,"lang":"en","type":"article","venue":"Gut Microbes","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research; Medical Research Council; National Institute for Health and Care Research","keywords":"Biology; Immunoglobulin A; Immunology; Firmicutes; Microbiome; Feces; Gut flora; Immune system; Microbiology; Transplantation; Fecal bacteriotherapy; Dysbiosis; Immunoglobulin G; Bacteria; Antibiotics; Clostridium difficile; Genetics; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000224084,0.0003193775,0.0005269508,0.0002495149,0.000132997,0.00005909955,0.000124157,0.0002121596,0.0000716139],"category_scores_gemma":[0.0002169376,0.0003106657,0.0003115215,0.0006359259,0.00005335247,0.00008824885,0.00004499107,0.0003997481,0.00005261613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002232862,"about_ca_system_score_gemma":0.0001582265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001713999,"about_ca_topic_score_gemma":0.0005718893,"domain_scores_codex":[0.9980015,0.00007070083,0.0004533502,0.0005967451,0.0002614211,0.0006163522],"domain_scores_gemma":[0.9992214,0.0001450322,0.00008374157,0.0002016637,0.0001087009,0.0002394709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001393494,0.0002765855,0.004320203,0.000729976,0.00007945941,0.00006760867,0.0007309761,0.00002293121,0.9817775,0.00001161699,0.002924687,0.007664961],"study_design_scores_gemma":[0.004524365,0.001290492,0.006892737,0.0004104931,0.0001954844,0.00004981755,0.0001652679,0.0004291686,0.9720104,0.000007443221,0.01366514,0.0003591571],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990262,0.001262238,0.0002853149,0.005966162,0.0003239999,0.001405816,0.0002037891,0.0001392542,0.0001514098],"genre_scores_gemma":[0.9961849,0.001379219,0.0004498614,0.0005477984,0.0004844291,0.0001190785,0.0006777894,0.00005868801,0.00009827528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01074046,"threshold_uncertainty_score":0.9999346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03082403034012747,"score_gpt":0.2950056462968514,"score_spread":0.2641816159567239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}