{"id":"W3115045672","doi":"10.3390/cancers13010042","title":"The Nuclear Pore Complex and mRNA Export in Cancer","year":2020,"lang":"en","type":"review","venue":"Cancers","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institutes of Health; Leukemia and Lymphoma Society","keywords":"Nuclear export signal; RNA; Messenger RNA; Biology; Nuclear pore; Translation (biology); Cell biology; Transcription (linguistics); Cancer; Gene expression; Cytoplasm; Gene; Computational biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003936073,0.0001598043,0.0003098877,0.00001538848,0.00007045982,0.00002266684,0.0001313359,0.0001571108,0.00004352623],"category_scores_gemma":[0.00001146994,0.0001098634,0.00009088926,0.00007386794,0.00008014217,0.000001130167,0.0000706322,0.0001581597,0.000003818595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001414255,"about_ca_system_score_gemma":0.0003024833,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006918384,"about_ca_topic_score_gemma":0.000112106,"domain_scores_codex":[0.9993458,0.00002901615,0.0001608786,0.0002694489,0.00005539806,0.0001394827],"domain_scores_gemma":[0.9996578,0.000005236353,0.00009590044,0.0001762567,0.00001278464,0.00005209466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001423061,5.95615e-7,0.000004704557,0.0004282536,0.00005885815,0.000006087319,0.00001941195,0.000001212138,0.00004572458,0.00005576286,0.02080598,0.9785592],"study_design_scores_gemma":[0.00007994888,0.00004222132,0.00002422291,0.0002338095,0.0000563579,0.00001445309,0.00002811075,0.000006021724,0.000001742361,0.00000718532,0.9993771,0.0001287867],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001106141,0.9978991,8.129873e-7,0.00006910815,0.0003010808,0.0001910516,0.0000283845,0.000005852588,0.001394014],"genre_scores_gemma":[0.0003539038,0.9986381,0.00001783955,0.0002576494,0.0004157436,0.00002636032,0.00008574486,0.00003604631,0.0001685968],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9785712,"threshold_uncertainty_score":0.44801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0330118339387341,"score_gpt":0.3063003495733032,"score_spread":0.2732885156345691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}