{"id":"W3115158449","doi":"10.4252/wjsc.v12.i12.1474","title":"Novel insights for improving the therapeutic safety and efficiency of mesenchymal stromal cells","year":2020,"lang":"en","type":"review","venue":"World Journal of Stem Cells","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Mesenchymal stem cell; Regenerative medicine; Transplantation; Medicine; Cell therapy; Microvesicles; Regeneration (biology); Therapeutic approach; Homing (biology); Bioinformatics; Stem cell; Cell biology; Biology; microRNA; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004696492,0.0003478148,0.0009796619,0.0001058077,0.00009231007,0.00003842285,0.0006317454,0.0001657623,0.000005830821],"category_scores_gemma":[0.00001347819,0.0002204149,0.0006906627,0.0001791811,0.000164994,0.000006385578,0.0001816933,0.0003321832,0.00000126717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003059041,"about_ca_system_score_gemma":0.0004354636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":9.48262e-7,"about_ca_topic_score_gemma":0.000002291044,"domain_scores_codex":[0.9979639,0.0001548609,0.001068249,0.0003123857,0.0002579241,0.000242702],"domain_scores_gemma":[0.9976875,0.0001783286,0.001470952,0.0003523453,0.0001538988,0.0001569282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000186271,0.0001557365,0.000001234996,0.006418256,0.0004633305,0.00001908122,0.00008577861,0.00002641308,0.3677075,0.0001402426,0.0001618635,0.6246343],"study_design_scores_gemma":[0.0006556653,0.000470309,0.000001310779,0.00111821,0.001154133,0.00008473555,0.00006287238,0.00004477983,0.04906942,0.000009698474,0.9470522,0.0002766662],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003197443,0.9921611,0.006277083,0.00002551965,0.0003827414,0.0006350944,0.00009356551,0.00000238973,0.0001027755],"genre_scores_gemma":[0.01092402,0.9867631,0.001027691,0.00005327796,0.0005537166,0.000007248711,0.00001004732,0.00006865804,0.0005922674],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9468904,"threshold_uncertainty_score":0.8988257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02097652453864518,"score_gpt":0.2679377012986301,"score_spread":0.2469611767599849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}