{"id":"W3115183047","doi":"10.1182/blood.2020009217","title":"Long-term outcomes with emicizumab prophylaxis for hemophilia A with or without FVIII inhibitors from the HAVEN 1-4 studies","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":289,"is_retracted":false,"has_abstract":true,"ca_institutions":"Roche (Canada)","funders":"Chugai Pharmaceutical; F. Hoffmann-La Roche","keywords":"Medicine; Adverse effect; Confidence interval; Internal medicine; Interquartile range; Hemostasis; Bleed; Surgery; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009678786,0.0003132018,0.000649955,0.00004108118,0.0002129566,0.00003992783,0.0001789974,0.00008436236,0.00003697108],"category_scores_gemma":[0.0002084737,0.0001191299,0.0001125095,0.0002625743,0.0002645592,0.0000694553,0.00008435416,0.0002551774,0.00002538762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004078902,"about_ca_system_score_gemma":0.0002563026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003133004,"about_ca_topic_score_gemma":0.0001955636,"domain_scores_codex":[0.9983187,0.00004230627,0.0002434974,0.0004756473,0.000525842,0.0003939748],"domain_scores_gemma":[0.998831,0.0002653897,0.00008341739,0.0004003711,0.0002030424,0.0002167393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003694772,0.0005734354,0.9865683,0.0002876428,0.002264205,0.0004169902,0.003566173,4.455173e-7,0.0006398238,0.000006655771,0.0005257981,0.001455767],"study_design_scores_gemma":[0.115764,0.05417424,0.7084422,0.002881162,0.007430921,0.0004251098,0.01012319,0.0001031881,0.09692009,0.00009800176,0.002031322,0.001606603],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9820374,0.0009608134,0.00001950701,0.0142135,0.00003906822,0.002473097,0.00004850085,0.0001051283,0.0001030158],"genre_scores_gemma":[0.9947235,0.00008023657,0.001484211,0.0006750108,0.0005097947,0.0003272367,0.00004638291,0.00006454107,0.002089081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2781261,"threshold_uncertainty_score":0.4857975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07264896458015811,"score_gpt":0.3371038152387838,"score_spread":0.2644548506586257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}