{"id":"W3115183047","doi":"10.1182/blood.2020009217","title":"Long-term outcomes with emicizumab prophylaxis for hemophilia A with or without FVIII inhibitors from the HAVEN 1-4 studies","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":289,"is_retracted":false,"has_abstract":true,"ca_institutions":"Roche (Canada)","funders":"Chugai Pharmaceutical; F. Hoffmann-La Roche","keywords":"Medicine; Adverse effect; Confidence interval; Internal medicine; Interquartile range; Hemostasis; Bleed; Surgery; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01351069,0.0005377208,0.00148438,0.0004573007,0.0004897525,0.001314729,0.0004539776,0.0008452539,0.002630602],"category_scores_gemma":[0.01079664,0.000213954,0.004284547,0.0007230296,0.0003285269,0.001120724,0.0008028322,0.001863013,0.0002507264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006903823,"about_ca_system_score_gemma":0.0006516268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001036717,"about_ca_topic_score_gemma":0.002333609,"domain_scores_codex":[0.9959666,0.00206686,0.0005756616,0.0004591689,0.0006041582,0.0003274883],"domain_scores_gemma":[0.9894979,0.003877698,0.004242922,0.0007236135,0.000953096,0.0007048087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2147025,0.002272804,0.3719801,0.01519931,0.08870357,0.0004837044,0.0006705648,0.004076682,0.003098183,0.001799159,0.01491521,0.2820982],"study_design_scores_gemma":[0.01956005,0.05068432,0.835916,0.006593791,0.05391511,0.001502841,0.0003404361,0.001586995,0.002281735,0.001695271,0.02574573,0.0001777636],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7875344,0.1922886,0.001909574,0.001133129,0.0003250579,0.0005765932,0.008715285,0.00004482418,0.007472725],"genre_scores_gemma":[0.9705576,0.01857831,0.0006843983,0.0006617891,0.0002736381,0.0006061191,0.007360422,0.00001885222,0.001258906],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01351069,"threshold_uncertainty_score":0.0714522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07264896458015811,"score_gpt":0.3371038152387838,"score_spread":0.2644548506586257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}