{"id":"W3115276079","doi":"10.3390/ijms22010142","title":"Chaperone-Assisted Mitotic Actin Remodeling by BAG3 and HSPB8 Involves the Deacetylase HDAC6 and Its Substrate Cortactin","year":2020,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Université Laval","keywords":"Cortactin; Cell biology; Mitosis; Biology; BAG3; Actin remodeling; Nocodazole; HDAC6; Midbody; Actin; Actin cytoskeleton; Cytoskeleton; Cell division; Autophagy; Histone deacetylase; Cell; Histone; Cytokinesis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008770867,0.0002921576,0.0001736084,0.000135874,0.0001880537,0.0003135429,0.0002170416,0.0001943436,0.0010035],"category_scores_gemma":[0.000051004,0.0001580737,0.0002610046,0.0001344042,0.0001973759,0.0001862593,0.0003073144,0.0003282464,0.0004051941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000310665,"about_ca_system_score_gemma":0.0001819614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005992174,"about_ca_topic_score_gemma":0.001116976,"domain_scores_codex":[0.9999191,0.000007524114,0.000004797336,0.00002197764,0.00002142086,0.00002524177],"domain_scores_gemma":[0.9999561,0.000002311893,0.0000170926,0.000006039512,0.000005830564,0.00001266881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001158067,0.00001250604,0.0005514842,0.00003189702,0.00000875718,0.00004537274,0.00001254956,0.00006971656,0.9964025,0.000194636,0.00007650121,0.002478217],"study_design_scores_gemma":[0.00002800015,0.0001095918,0.01803645,0.000006950471,0.00002437929,0.0003603906,0.00004296577,0.002094937,0.9724538,0.0002174358,0.00661617,0.000008925893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864829,0.003058287,0.007369758,0.0001737895,0.00005127727,0.00001504452,0.0003760411,0.0002691355,0.002203631],"genre_scores_gemma":[0.9965264,0.000473382,0.0008866598,0.000038185,0.000006402427,0.00001067966,0.0003168298,0.00002279104,0.001718626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0010035,"threshold_uncertainty_score":0.003357053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03054402663125982,"score_gpt":0.2858377542693956,"score_spread":0.2552937276381357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}