{"id":"W3115366055","doi":"10.1093/neuonc/noaa300","title":"Transcription factor networks of oligodendrogliomas treated with adjuvant radiotherapy or observation inform prognosis","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kingston General Hospital; Queen's University; Toronto Western Hospital; Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Medicine; Cohort; Oncology; Radiation therapy; Internal medicine; Adjuvant; Oligodendroglioma; Adjuvant therapy; Gene signature; Overall survival; Transcription factor; Adjuvant radiotherapy; Glioma; Cancer; Cancer research; Gene expression; Gene; Biology; Astrocytoma; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004076593,0.0002222182,0.0006145558,0.0001035757,0.00004195028,0.00001033691,0.0000752544,0.000183897,0.0001781545],"category_scores_gemma":[0.00004017784,0.0001436877,0.0001112472,0.0005236637,0.00007424308,0.0001152895,0.000009240041,0.0001645666,0.000004771727],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001471061,"about_ca_system_score_gemma":0.0001571692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004523823,"about_ca_topic_score_gemma":0.00005241065,"domain_scores_codex":[0.9987497,0.00006560123,0.0004040956,0.0002997917,0.0002222046,0.0002585895],"domain_scores_gemma":[0.9991421,0.0001427088,0.0002049881,0.000166433,0.0001357191,0.0002080969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006560052,0.001417489,0.2331385,0.0001376166,0.0004688766,0.000716613,0.001643353,0.000396524,0.635236,0.00007288013,0.0009863075,0.1192257],"study_design_scores_gemma":[0.03049332,0.05216496,0.3613719,0.0001753251,0.001106275,0.0004364001,0.0002723687,0.02025549,0.4339989,0.00000353048,0.09925018,0.000471447],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923056,0.0003467927,0.0003840472,0.005354935,0.00009315349,0.001164459,0.00001927593,0.0001142867,0.0002174767],"genre_scores_gemma":[0.9954419,0.0005573216,0.0008868615,0.002671402,0.0001419829,0.0001778475,0.00007677442,0.00003829346,0.000007683526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2012372,"threshold_uncertainty_score":0.5859415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05016786983759589,"score_gpt":0.2905154291076138,"score_spread":0.2403475592700179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}