{"id":"W3115410759","doi":"10.1053/j.gastro.2020.12.031","title":"STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD","year":2021,"lang":"en","type":"review","venue":"Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2666,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"Celgene; Biogen; Janssen Pharmaceuticals; Gilead Sciences; Medtronic; Amgen; Pfizer; Shire; Bristol-Myers Squibb; Roche; Meso Scale Diagnostics; Takeda Pharmaceutical Company; AbbVie; Merck","keywords":"STRIDE; Medicine; Physical medicine and rehabilitation; Disease; Inflammatory bowel disease; Intensive care medicine; Physical therapy; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002081835,0.001478749,0.00301642,0.002520657,0.0003184905,0.002048102,0.001424046,0.001920201,0.003738029],"category_scores_gemma":[0.002499953,0.0004226771,0.001057336,0.002647685,0.0004944755,0.00182593,0.001279891,0.004124258,0.003061348],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001089592,"about_ca_system_score_gemma":0.002480962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00153759,"about_ca_topic_score_gemma":0.004270286,"domain_scores_codex":[0.9995241,0.0001073718,0.00009203779,0.00005342388,0.0001688548,0.00005429966],"domain_scores_gemma":[0.9988797,0.000511791,0.0001442539,0.00002035274,0.0002945127,0.0001493875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000152393,0.00007318344,0.0001843212,0.01406233,0.0001475712,0.0001209363,0.00003364627,0.0003240836,0.0005948027,0.002191784,0.1453271,0.8367878],"study_design_scores_gemma":[0.0001190399,0.0001562117,0.0005674001,0.0072029,0.0002977413,0.0004815111,0.00002907583,0.0001043537,0.0001713952,0.001262853,0.9895813,0.0000262326],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006051722,0.9960587,0.0002096321,0.001248326,0.001521726,0.00001592155,0.00008255276,0.00001930811,0.0007833553],"genre_scores_gemma":[0.0002574495,0.9958001,0.0004638146,0.001662241,0.0009651665,0.00002182573,0.0001506063,0.000006813174,0.0006719749],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003738029,"threshold_uncertainty_score":0.01250494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02900265889026595,"score_gpt":0.3059937723607599,"score_spread":0.276991113470494,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}