{"id":"W3115888003","doi":"10.1097/shk.0000000000001701","title":"Mesenchymal Stem/Stromal Cells Increase Cardiac miR-187-3p Expression in a Polymicrobial Animal Model of Sepsis","year":2020,"lang":"en","type":"article","venue":"Shock","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Ottawa Hospital; University of Ottawa; University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Mesenchymal stem cell; Sepsis; microRNA; Transcriptome; Downregulation and upregulation; Ligation; Systemic administration; Pathophysiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002632331,0.0004928706,0.0004385771,0.0005902714,0.000148399,0.0002832332,0.0001638125,0.0003084451,0.001641958],"category_scores_gemma":[0.000130967,0.00021373,0.0003624282,0.0002308287,0.0003595644,0.0001828461,0.0001849085,0.0009886995,0.0003078804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002214595,"about_ca_system_score_gemma":0.0002569729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002375619,"about_ca_topic_score_gemma":0.0003789627,"domain_scores_codex":[0.9997849,0.00003708285,0.00002072093,0.00004239544,0.00006421522,0.00005064136],"domain_scores_gemma":[0.999801,0.00002495598,0.00007740013,0.00001435672,0.00001814509,0.0000642576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008274953,0.0001096557,0.0002248371,0.0000551788,0.000009917706,0.00003667835,0.00001452025,0.00009930289,0.9976519,0.00003774512,0.00005548702,0.0008773505],"study_design_scores_gemma":[0.00009855448,0.002457965,0.007463412,0.00001774934,0.00005335556,0.000116346,0.00008669106,0.002070271,0.9866331,0.00006782438,0.0009260249,0.000008744155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936396,0.0009983459,0.003402839,0.0001929752,0.00008499924,0.00005585295,0.0006978347,0.0001272282,0.0008002317],"genre_scores_gemma":[0.9934471,0.0007624191,0.003234886,0.0001486269,0.00002598203,0.0001354279,0.0006549581,0.00003183543,0.001558792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001641958,"threshold_uncertainty_score":0.005492926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04314861779104872,"score_gpt":0.2876755668441816,"score_spread":0.2445269490531328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}