{"id":"W3115991508","doi":"10.1080/15476286.2020.1868150","title":"An epigenetic ‘extreme makeover’: the methylation of flaviviral RNA (and beyond)","year":2020,"lang":"en","type":"review","venue":"RNA Biology","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Fonds de recherche du Québec – Nature et technologies; Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Deutsche Forschungsgemeinschaft","keywords":"Biology; RNA; Flavivirus; RNA methylation; Epigenetics; Dengue fever; Viral replication; Methylation; DNA methylation; RNA editing; Genetics; Subgenomic mRNA; Translation (biology); Virology; Computational biology; Messenger RNA; Gene; Virus; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001983074,0.0002567735,0.0006084841,0.00004573929,0.00007153398,0.000015556,0.0003768084,0.0004182009,0.00002821859],"category_scores_gemma":[0.00004883618,0.0001701416,0.0002103773,0.0001249974,0.0002104443,0.000002597739,0.0001046346,0.0001633016,0.000009576701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000144373,"about_ca_system_score_gemma":0.0001694823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002199037,"about_ca_topic_score_gemma":0.00001556252,"domain_scores_codex":[0.9985321,0.0003283526,0.0004197508,0.0004716023,0.00006004937,0.0001881764],"domain_scores_gemma":[0.9989363,0.00003306469,0.000336795,0.0005646646,0.00006217982,0.00006699411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000008512499,0.00001861948,0.000008337352,0.000297039,0.0001252345,4.840549e-7,0.00001964999,0.000001268485,0.03397281,0.0009352208,0.0001718219,0.964441],"study_design_scores_gemma":[0.0001063684,0.0003035619,0.00003024019,0.00006864332,0.0002371328,0.000009212443,0.00001318979,0.00001458039,0.00165188,0.0002243839,0.997144,0.000196743],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006405076,0.9966952,0.001133961,0.000113907,0.0001697854,0.0003587663,0.0001378383,0.000007187221,0.0007429089],"genre_scores_gemma":[0.01155869,0.9868661,0.000252327,0.0001123567,0.0003733156,0.00007089042,0.0005861843,0.00003221412,0.0001479123],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9969723,"threshold_uncertainty_score":0.6938174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04667347196236467,"score_gpt":0.3354646960197854,"score_spread":0.2887912240574207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}