{"id":"W3116001976","doi":"","title":"Dual Adeno-Associated Virus Vector mediated gene therapy for autosomal recessive Stargardt Disease","year":2019,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Adeno-associated virus; Genetic enhancement; Stargardt disease; Vector (molecular biology); Gene; Genetics; Dual (grammatical number); Biology; Virology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001961013,0.0003578257,0.0003983336,0.0004315429,0.0002050996,0.0004230901,0.0002757175,0.0004594723,0.0009753922],"category_scores_gemma":[0.0001059098,0.0001319719,0.0003217207,0.0002452829,0.0003999925,0.0002796649,0.0002655299,0.0007755048,0.0001599542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005105228,"about_ca_system_score_gemma":0.0004286718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007552336,"about_ca_topic_score_gemma":0.0009490172,"domain_scores_codex":[0.9998432,0.00001933252,0.00001466326,0.00003127183,0.00006006108,0.00003135596],"domain_scores_gemma":[0.9999448,0.00001007126,0.00001877615,0.000006527246,0.000005144754,0.00001466114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003565137,0.00009052199,0.0001667182,0.00006743088,0.00001367187,0.0006302659,0.00003835111,0.0001797498,0.9876758,0.002114791,0.0001820568,0.008484144],"study_design_scores_gemma":[0.0003089763,0.001739348,0.002364887,0.00002371846,0.0001270741,0.005619035,0.00006879627,0.004426722,0.9682587,0.0006798702,0.01635325,0.0000295073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9756355,0.004659737,0.01439572,0.0003842206,0.0002404765,0.00008380461,0.0003500862,0.0002574863,0.003992905],"genre_scores_gemma":[0.9860393,0.001876702,0.00696191,0.00004153504,0.00001740595,0.00004361274,0.0001753436,0.00002746401,0.004816702],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009753922,"threshold_uncertainty_score":0.00370419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02136061755047713,"score_gpt":0.3067021952383694,"score_spread":0.2853415776878923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}