{"id":"W3116108534","doi":"10.1016/j.bpj.2020.12.015","title":"Correlating the Structure and Activity of Y. pestis Ail in a Bacterial Cell Envelope","year":2020,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Yersinia bacterium, plague, ectoparasites research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; National Institute of General Medical Sciences; National Institutes of Health; National Cancer Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Yersinia pestis; Bacterial outer membrane; Cell envelope; Virulence; Biology; Escherichia coli; Bacterial cell structure; Inner membrane; Function (biology); Vitronectin; Human pathogen; Membrane protein; Cell biology; Biophysics; Microbiology; Computational biology; Bacteria; Membrane; Cell; Biochemistry; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001662985,0.0001689612,0.0001314375,0.0001857454,0.000202715,0.0005275483,0.0001820608,0.0002232575,0.0007599044],"category_scores_gemma":[0.0003068963,0.0001262048,0.0001707956,0.0002526132,0.0002450396,0.0003504106,0.00016585,0.0005023051,0.0003396845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005121754,"about_ca_system_score_gemma":0.0001713722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001316637,"about_ca_topic_score_gemma":0.0008503011,"domain_scores_codex":[0.9999235,0.00001338339,0.000004414069,0.00001407033,0.00001879488,0.00002588169],"domain_scores_gemma":[0.9998496,0.00004306372,0.00003229999,0.00001414333,0.00003443012,0.00002645873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001879262,0.00003190569,0.001318102,0.00001657228,0.000006213034,0.00006290533,0.00003431247,0.0001675397,0.9972724,0.0001693646,0.00003643457,0.0006963354],"study_design_scores_gemma":[0.00001776072,0.0001847051,0.02323647,0.000007970509,0.00001572723,0.0002011355,0.0001788703,0.004794476,0.9693193,0.0001371638,0.001899303,0.000007027291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978676,0.0003738593,0.000784427,0.00009633754,0.0000065455,0.000005457633,0.0001178148,0.000008625479,0.0007392745],"genre_scores_gemma":[0.9975992,0.0001797102,0.0006433423,0.00004350248,0.000004730494,0.000005470143,0.0005911836,0.000005614302,0.0009272283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001316637,"threshold_uncertainty_score":0.003716171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01186504408249497,"score_gpt":0.2504626482788304,"score_spread":0.2385976041963354,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}