{"id":"W3116108856","doi":"10.1016/j.vaccine.2020.12.035","title":"Immunogenicity and safety of the 13-valent pneumococcal conjugate vaccine in 23-valent pneumococcal polysaccharide vaccine-naïve and previously immunized adult patients with severe chronic kidney disease","year":2020,"lang":"en","type":"article","venue":"Vaccine","topic":"Pneumonia and Respiratory Infections","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lakehead University; NOSM University","funders":"Pfizer Canada; Northern Ontario Academic Medicine Association","keywords":"Immunogenicity; Pneumococcal polysaccharide vaccine; Serotype; Medicine; Pneumococcal conjugate vaccine; Streptococcus pneumoniae; Immunization; Immunology; Pneumococcal vaccine; Antibody; Immunoglobulin G; Virology; Microbiology; Biology; Pneumococcal disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000747838,0.000292884,0.0004601644,0.0002209724,0.0003351874,0.0005445692,0.0001657387,0.000488318,0.001016876],"category_scores_gemma":[0.002611243,0.0001964408,0.0006707266,0.0002466548,0.000303807,0.0006035187,0.0002204457,0.0006940481,0.0002283035],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003352037,"about_ca_system_score_gemma":0.0003282402,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001651546,"about_ca_topic_score_gemma":0.001104659,"domain_scores_codex":[0.9995766,0.000138939,0.00003819711,0.00007308386,0.00005637109,0.0001167377],"domain_scores_gemma":[0.999162,0.0002778935,0.000163533,0.00006254562,0.00008845264,0.0002455959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01859748,0.00164938,0.9625164,0.00003995678,0.0003159303,0.0005618354,0.0004628815,0.0003597041,0.006089071,0.00005405389,0.0002760551,0.009077168],"study_design_scores_gemma":[0.0003322192,0.009850889,0.9878106,0.000006311055,0.00009454156,0.0004671801,0.0001998286,0.0005608073,0.0004406907,0.00003803303,0.0001869971,0.00001179877],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997481,0.00006292781,0.000009356283,0.00001587469,0.000005377085,0.000002638024,0.00002883417,5.687852e-7,0.0001264218],"genre_scores_gemma":[0.9997752,0.00003072543,0.000007499013,0.00002960839,0.00001340963,0.000002375905,0.00007017933,4.285376e-7,0.00007046718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001651546,"threshold_uncertainty_score":0.003955007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005943315585700329,"score_gpt":0.2160195856153442,"score_spread":0.2100762700296439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}