{"id":"W3116267620","doi":"10.1002/ajoc.202000482","title":"Diastereoselective Rhodium‐Catalyzed [(3+2+2)] Carbocyclization Reactions with Tethered Alkynylidenecyclopropanes: Synthesis of the Tremulane Sesquiterpene Natural Products","year":2020,"lang":"en","type":"article","venue":"Asian Journal of Organic Chemistry","topic":"Cyclopropane Reaction Mechanisms","field":"Chemistry","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Institute for Basic Science; Royal Society; Government of Ontario","keywords":"Chemistry; Stereocenter; Diastereomer; Rhodium; Stereochemistry; Intramolecular force; Sesquiterpene; Allene; Ligand (biochemistry); Cope rearrangement; Asymmetric induction; Combinatorial chemistry; Catalysis; Enantioselective synthesis; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002104976,0.000458888,0.0001724012,0.0002028103,0.0001287559,0.00017311,0.0003369507,0.0002578316,0.002006234],"category_scores_gemma":[0.0001634222,0.0001295924,0.0002116643,0.0001448353,0.0002025593,0.0002723864,0.0003031124,0.0004407502,0.0006952918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002203965,"about_ca_system_score_gemma":0.0003545671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004256441,"about_ca_topic_score_gemma":0.001178949,"domain_scores_codex":[0.9998964,0.00001737155,0.00000863328,0.0000222445,0.0000198158,0.00003563873],"domain_scores_gemma":[0.9999408,0.000009470547,0.00001539721,0.00001119321,0.00000858152,0.0000146358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008054443,0.00005997558,0.0001255112,0.000196364,0.0000185008,0.0004496114,0.0000983012,0.0007064691,0.9894955,0.00168805,0.0002046392,0.006876583],"study_design_scores_gemma":[0.00003523338,0.0003377143,0.0004816666,0.000009859875,0.00001326192,0.0003105979,0.00003254307,0.0007986035,0.9926435,0.0001560281,0.005166656,0.000014213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9540275,0.002145399,0.02560394,0.0002188873,0.000118449,0.0003239368,0.0004861909,0.0003002938,0.01677536],"genre_scores_gemma":[0.9872029,0.00103963,0.008675905,0.00004529979,0.00001245413,0.00006692718,0.0001576081,0.00002640447,0.0027729],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002006234,"threshold_uncertainty_score":0.006711543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007593887996624744,"score_gpt":0.1940738297063589,"score_spread":0.1864799417097341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}