{"id":"W3116496294","doi":"10.21203/rs.3.rs-79022/v1","title":"Successful treatment of COVID-19 with remdesivir in the absence of humoral immunity","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; National Institute for Health and Care Research; UK Research and Innovation; Horizon 2020 Framework Programme; NIHR Cambridge Biomedical Research Centre; Wellcome Trust; NIHR Oxford Biomedical Research Centre; NHS Blood and Transplant","keywords":"Medicine; Immunology; Coronavirus disease 2019 (COVID-19); Coronavirus; Antibody; Disease; Immunity; Hydroxychloroquine; Pandemic; In vivo; Virology; Immune system; Infectious disease (medical specialty); Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006014027,0.0003723941,0.0005681758,0.0001673938,0.0002927833,0.0003216594,0.0002052058,0.0005099307,0.001162745],"category_scores_gemma":[0.0005319443,0.00009950194,0.0002866753,0.00007641831,0.0002965717,0.0002020799,0.0001913645,0.0008209652,0.0004798545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001933658,"about_ca_system_score_gemma":0.0002152189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001880298,"about_ca_topic_score_gemma":0.0002111583,"domain_scores_codex":[0.9997827,0.00008452158,0.00002139189,0.00003088419,0.00003180432,0.00004876274],"domain_scores_gemma":[0.9997968,0.00007553802,0.00002262172,0.00004836692,0.0000185163,0.00003815601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"case_report","study_design_scores_codex":[0.01565859,0.007571522,0.004456857,0.0003320852,0.0001772148,0.007005448,0.0002700884,0.001170591,0.8099248,0.001128914,0.003199356,0.1491046],"study_design_scores_gemma":[0.003381894,0.1228373,0.0246933,0.00008186487,0.000217202,0.01415141,0.0001704038,0.004347718,0.776795,0.0008029154,0.05248146,0.00003945614],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841114,0.003537087,0.004274908,0.0006800299,0.0003367458,0.0003628855,0.0003750417,0.0001626854,0.006159274],"genre_scores_gemma":[0.9952968,0.0005226108,0.001544374,0.0002678039,0.00008494327,0.00007008057,0.00037988,0.00002053311,0.001812895],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001162745,"threshold_uncertainty_score":0.00388974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2542724271720346,"score_gpt":0.5447574928599491,"score_spread":0.2904850656879145,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}