{"id":"W3116678535","doi":"","title":"NLRP3 inflammasome contributes to retinal ganglion cell (RGC) death during glaucoma pathogenesis in DBA/2J mouse model.","year":2019,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Inflammasome; Retinal ganglion cell; Pathogenesis; Glaucoma; Retinal; Ganglion; Ophthalmology; Medicine; Biology; Neuroscience; Immunology; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003900996,0.000715057,0.0004151475,0.001501986,0.0004390671,0.0005880256,0.0003091962,0.001124014,0.003506887],"category_scores_gemma":[0.0001742769,0.0003971597,0.0006534412,0.0004378813,0.0007574726,0.0008215189,0.0003630413,0.002253847,0.0006809806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003821875,"about_ca_system_score_gemma":0.0003373071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001014834,"about_ca_topic_score_gemma":0.001397237,"domain_scores_codex":[0.9995603,0.00005893885,0.00006015298,0.00009731516,0.0001185749,0.0001047217],"domain_scores_gemma":[0.9996496,0.0000184209,0.0001471156,0.00002850667,0.00002938445,0.0001267805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001587761,0.0002491806,0.002231762,0.0002492302,0.000040748,0.0008129713,0.00008768091,0.00006850297,0.9903594,0.0007298667,0.000739784,0.002843069],"study_design_scores_gemma":[0.0004761978,0.00208736,0.08289691,0.0001565413,0.000423945,0.007452046,0.0008142345,0.003020825,0.8911166,0.00181938,0.009672208,0.00006368146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9762186,0.00913001,0.005332305,0.001279439,0.0003938011,0.000116391,0.002751671,0.0004237823,0.004354006],"genre_scores_gemma":[0.9828365,0.003723717,0.002565042,0.0004834616,0.00007287872,0.0001644709,0.001213373,0.00007998499,0.008860573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003506887,"threshold_uncertainty_score":0.01173174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01200396302135203,"score_gpt":0.2682498926098908,"score_spread":0.2562459295885388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}