{"id":"W3116750141","doi":"10.1093/humupd/dmaa052","title":"Is there an association between paternal age and aneuploidy? Evidence from young donor oocyte-derived embryos: a systematic review and individual patient data meta-analysis","year":2020,"lang":"en","type":"review","venue":"Human Reproduction Update","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"CReATe Fertility Centre; University of Toronto","funders":"","keywords":"Aneuploidy; Meta-analysis; Medicine; Advanced maternal age; Live birth; Gynecology; Obstetrics; Systematic review; Pregnancy; MEDLINE; Biology; Chromosome; Genetics; Internal medicine; Fetus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0202624,0.002432841,0.02173692,0.006448292,0.0006828663,0.00370555,0.002880767,0.002764087,0.005374454],"category_scores_gemma":[0.06880892,0.001481598,0.03698007,0.007665029,0.001035393,0.002310991,0.001838418,0.001999135,0.0004198756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003192542,"about_ca_system_score_gemma":0.005335982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007957988,"about_ca_topic_score_gemma":0.01776145,"domain_scores_codex":[0.9839814,0.007530153,0.00527617,0.001398433,0.001414162,0.0003996923],"domain_scores_gemma":[0.9411918,0.04716653,0.007041127,0.001338079,0.002876152,0.0003863775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.000945096,0.00001607617,0.002605624,0.6704133,0.3159075,0.0001286488,0.00009147797,0.0002470633,0.0001229363,0.0001315535,0.0005103205,0.008880523],"study_design_scores_gemma":[0.0004573568,0.0001809515,0.003250305,0.08944454,0.9037535,0.0001205161,0.00006081787,0.0001142822,0.00008533534,0.0002510368,0.00225397,0.00002749193],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002417088,0.995494,0.0004738685,0.000201342,0.0001338822,0.0003383869,0.0006862085,0.00001606077,0.0002391338],"genre_scores_gemma":[0.1106645,0.8817071,0.002305062,0.001595684,0.0002585546,0.002056895,0.001070063,0.00003547203,0.0003066394],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02173692,"threshold_uncertainty_score":0.1071591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2807517724556136,"score_gpt":0.3820276612978011,"score_spread":0.1012758888421876,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}