{"id":"W3116811089","doi":"10.1016/j.cryobiol.2020.10.037","title":"Immediate evaluations of post-thaw membrane integrity can underestimate cell survival under conditions that promote intracellular ice formation","year":2020,"lang":"en","type":"article","venue":"Cryobiology","topic":"Freezing and Crystallization Processes","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; University of Alberta","keywords":"Ice formation; Intracellular; Cell biology; Membrane integrity; Biophysics; Chemistry; Membrane; Biology; Biochemistry; Geology; Atmospheric sciences","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009879806,0.0007504201,0.0005096632,0.0003478882,0.0008699504,0.001228367,0.0004307634,0.0008317124,0.001757129],"category_scores_gemma":[0.00172185,0.000303315,0.0003198729,0.00031838,0.0006011139,0.001233609,0.0006526393,0.001585898,0.0007688049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007059947,"about_ca_system_score_gemma":0.0005484244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002715211,"about_ca_topic_score_gemma":0.003673492,"domain_scores_codex":[0.9995081,0.00007108713,0.00003935764,0.00008617587,0.0001999484,0.00009536571],"domain_scores_gemma":[0.9987687,0.0004077605,0.0001797629,0.00015293,0.0003943213,0.0000964721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001858606,0.00005862753,0.006308752,0.0001454927,0.00003433811,0.0001300066,0.0003066161,0.0003205804,0.9860059,0.000219168,0.0002711491,0.00601361],"study_design_scores_gemma":[0.000004523083,0.0001757806,0.03012875,0.00003134107,0.00005566457,0.0002281505,0.0003380759,0.001975379,0.9645644,0.0003389262,0.002145754,0.00001331836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9408065,0.003743622,0.04656482,0.0004116651,0.0001626411,0.0001356918,0.0007945041,0.0003665538,0.007014092],"genre_scores_gemma":[0.979115,0.002109873,0.0131999,0.0003030894,0.00002935616,0.0001937466,0.001016258,0.000159835,0.003872843],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002715211,"threshold_uncertainty_score":0.00587815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03591868880790542,"score_gpt":0.2577206444742515,"score_spread":0.2218019556663461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}